TY - JOUR
T1 - Fragile phagocytes
T2 - FMRP positively regulates engulfment activity
AU - Logan, Mary A.
N1 - Publisher Copyright:
© 2017 Logan.
PY - 2017/3/6
Y1 - 2017/3/6
N2 - Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.
AB - Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.
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U2 - 10.1083/jcb.201702034
DO - 10.1083/jcb.201702034
M3 - Article
C2 - 28228533
AN - SCOPUS:85021849199
VL - 216
SP - 531
EP - 533
JO - Journal of Cell Biology
JF - Journal of Cell Biology
SN - 0021-9525
IS - 3
ER -