Fragile phagocytes: FMRP positively regulates engulfment activity

Mary A. Logan

doi:10.1083/jcb.201702034

Fragile phagocytes: FMRP positively regulates engulfment activity

Mary A. Logan

Neurology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

Original language	English (US)
Pages (from-to)	531-533
Number of pages	3
Journal	The Journal of cell biology
Volume	216
Issue number	3
DOIs	https://doi.org/10.1083/jcb.201702034
State	Published - Mar 6 2017

ASJC Scopus subject areas

Cell Biology

Access to Document

10.1083/jcb.201702034

Fingerprint Dive into the research topics of 'Fragile phagocytes: FMRP positively regulates engulfment activity'. Together they form a unique fingerprint.

Cite this

@article{43ec3b85e5ff4b19bf1c0f0d551bc4ab,

title = "Fragile phagocytes: FMRP positively regulates engulfment activity",

abstract = "Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.",

author = "Logan, {Mary A.}",

note = "Publisher Copyright: {\textcopyright} 2017 Logan. Copyright: This record is sourced from MEDLINE{\textregistered}/PubMed{\textregistered}, a database of the U.S. National Library of Medicine",

year = "2017",

month = mar,

day = "6",

doi = "10.1083/jcb.201702034",

language = "English (US)",

volume = "216",

pages = "531--533",

journal = "Journal of Cell Biology",

issn = "0021-9525",

publisher = "Rockefeller University Press",

number = "3",

}

TY - JOUR

T1 - Fragile phagocytes

T2 - FMRP positively regulates engulfment activity

AU - Logan, Mary A.

PY - 2017/3/6

Y1 - 2017/3/6

N2 - Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

AB - Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

UR - http://www.scopus.com/inward/record.url?scp=85021849199&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021849199&partnerID=8YFLogxK

U2 - 10.1083/jcb.201702034

DO - 10.1083/jcb.201702034

M3 - Article

C2 - 28228533

AN - SCOPUS:85021849199

VL - 216

SP - 531

EP - 533

JO - Journal of Cell Biology

JF - Journal of Cell Biology

SN - 0021-9525

IS - 3

ER -

Fragile phagocytes: FMRP positively regulates engulfment activity

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this