Fragile phagocytes: FMRP positively regulates engulfment activity

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Abstract

Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

Original languageEnglish (US)
Pages (from-to)531-533
Number of pages3
JournalThe Journal of cell biology
Volume216
Issue number3
DOIs
Publication statusPublished - Mar 6 2017

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ASJC Scopus subject areas

  • Cell Biology

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