Fragile phagocytes: FMRP positively regulates engulfment activity

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

Original languageEnglish (US)
Pages (from-to)531-533
Number of pages3
JournalThe Journal of cell biology
Volume216
Issue number3
DOIs
StatePublished - Mar 6 2017

Fingerprint

Phagocytes
Fragile X Syndrome
Drosophila melanogaster
Innate Immunity
Immune System
Autism Spectrum Disorder

ASJC Scopus subject areas

  • Cell Biology

Cite this

Fragile phagocytes : FMRP positively regulates engulfment activity. / Logan, Mary.

In: The Journal of cell biology, Vol. 216, No. 3, 06.03.2017, p. 531-533.

Research output: Contribution to journalArticle

@article{43ec3b85e5ff4b19bf1c0f0d551bc4ab,
title = "Fragile phagocytes: FMRP positively regulates engulfment activity",
abstract = "Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.",
author = "Mary Logan",
year = "2017",
month = "3",
day = "6",
doi = "10.1083/jcb.201702034",
language = "English (US)",
volume = "216",
pages = "531--533",
journal = "Journal of Cell Biology",
issn = "0021-9525",
publisher = "Rockefeller University Press",
number = "3",

}

TY - JOUR

T1 - Fragile phagocytes

T2 - FMRP positively regulates engulfment activity

AU - Logan, Mary

PY - 2017/3/6

Y1 - 2017/3/6

N2 - Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

AB - Defective immune system function is implicated in autism spectrum disorders, including Fragile X syndrome. In this issue, O'Connor et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607093) demonstrate that phagocytic activity of systemic immune cells is compromised in a Drosophila melanogaster model of Fragile X, highlighting intriguing new mechanistic connections between FMRP, innate immunity, and abnormal development.

UR - http://www.scopus.com/inward/record.url?scp=85021849199&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021849199&partnerID=8YFLogxK

U2 - 10.1083/jcb.201702034

DO - 10.1083/jcb.201702034

M3 - Article

C2 - 28228533

AN - SCOPUS:85021849199

VL - 216

SP - 531

EP - 533

JO - Journal of Cell Biology

JF - Journal of Cell Biology

SN - 0021-9525

IS - 3

ER -