Forty-year survival with the starr-edwards heart valve prosthesis

Guangqiang Gao, Ying Xing Wu, Gary L. Grunkemeier, Anthony P. Furnary, Albert Starr

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Background and aim of the study: The study aim was to update an analysis of the long-term survival of heart valve replacement using the Starr-Edwards prosthesis. Methods: Cases of isolated aortic (AVR, n = 2,247) and mitral (MVR, n = 1,406) valve replacement with Starr-Edwards prostheses implanted between 1960 and 1997, with follow up to 2003, were reviewed. Introduced in 1965, the Models A1200/1260, M6120 are still in use (Current), while other models have been discontinued (Discontinued). For AVR, 938 valves were Discontinued, with a total follow up of 8,506 patient-years (pt-yr) and a maximum of 41 years; by comparison, 1,309 valves were Current, with a total follow up of 11,586 pt-yr and a maximum of 36.1 years. For MVR, 635 valves were Discontinued, with a total follow up of 6,454 pt-yr and maximum of 37.2 years; and 771 valves were Current, with a total follow up of 6,211 pt-yr and maximum of 37.0 years. Results: Kaplan-Meier (KM) survival at 10 years was 53% for AVR and 51% for MVR; KM survival at 20 years was 23% for both AVR and MVR; KM survival at 30 years was 8% for both AVR and MVR; KM sur-vival at 40 years was 4% for AVR. The standard error for all KM percentages was 1%. Four patients are cur-rently alive with their original valves, more than 40 years after implantation. Conclusion: This series of patients, who underwent valve replacement with the Starr-Edwards valve, now have a follow up extending beyond 40 years, thereby confirming the excellent durability of this valve.

Original languageEnglish (US)
Pages (from-to)91-96
Number of pages6
JournalJournal of Heart Valve Disease
Volume13
Issue number1
StatePublished - Jan 1 2004

    Fingerprint

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Gao, G., Wu, Y. X., Grunkemeier, G. L., Furnary, A. P., & Starr, A. (2004). Forty-year survival with the starr-edwards heart valve prosthesis. Journal of Heart Valve Disease, 13(1), 91-96.