Folding Biology of Cystic Fibrosis: A Consortium-Based Approach to Disease

William E. Balch, Ineke Braakman, Jeff Brodsky, Raymond Frizzell, William Guggino, Gergely L. Lukacs, Christopher Penland, Harvey Pollard, William Skach, Eric Sorscher, Philip Thomas

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
Original languageEnglish (US)
Title of host publicationProtein Misfolding Diseases: Current and Emerging Principles and Therapies
PublisherJohn Wiley and Sons
Pages425-452
Number of pages28
ISBN (Print)9780471799283
DOIs
StatePublished - Jul 2 2010

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Cystic Fibrosis

Keywords

  • CFTR folding, series of sequential steps - nascent polypeptide, targeted to endoplasmic reticulum (ER)
  • Cystic fibrosis folding biology - consortium-based approach to disease
  • Trafficking to cell surface - "minimal export threshold" embracing key fundamental properties of protein fold-folding kinetics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Balch, W. E., Braakman, I., Brodsky, J., Frizzell, R., Guggino, W., Lukacs, G. L., ... Thomas, P. (2010). Folding Biology of Cystic Fibrosis: A Consortium-Based Approach to Disease. In Protein Misfolding Diseases: Current and Emerging Principles and Therapies (pp. 425-452). John Wiley and Sons. https://doi.org/10.1002/9780470572702.ch19

Folding Biology of Cystic Fibrosis : A Consortium-Based Approach to Disease. / Balch, William E.; Braakman, Ineke; Brodsky, Jeff; Frizzell, Raymond; Guggino, William; Lukacs, Gergely L.; Penland, Christopher; Pollard, Harvey; Skach, William; Sorscher, Eric; Thomas, Philip.

Protein Misfolding Diseases: Current and Emerging Principles and Therapies. John Wiley and Sons, 2010. p. 425-452.

Research output: Chapter in Book/Report/Conference proceedingChapter

Balch, WE, Braakman, I, Brodsky, J, Frizzell, R, Guggino, W, Lukacs, GL, Penland, C, Pollard, H, Skach, W, Sorscher, E & Thomas, P 2010, Folding Biology of Cystic Fibrosis: A Consortium-Based Approach to Disease. in Protein Misfolding Diseases: Current and Emerging Principles and Therapies. John Wiley and Sons, pp. 425-452. https://doi.org/10.1002/9780470572702.ch19
Balch WE, Braakman I, Brodsky J, Frizzell R, Guggino W, Lukacs GL et al. Folding Biology of Cystic Fibrosis: A Consortium-Based Approach to Disease. In Protein Misfolding Diseases: Current and Emerging Principles and Therapies. John Wiley and Sons. 2010. p. 425-452 https://doi.org/10.1002/9780470572702.ch19
Balch, William E. ; Braakman, Ineke ; Brodsky, Jeff ; Frizzell, Raymond ; Guggino, William ; Lukacs, Gergely L. ; Penland, Christopher ; Pollard, Harvey ; Skach, William ; Sorscher, Eric ; Thomas, Philip. / Folding Biology of Cystic Fibrosis : A Consortium-Based Approach to Disease. Protein Misfolding Diseases: Current and Emerging Principles and Therapies. John Wiley and Sons, 2010. pp. 425-452
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