Fluorescent imaging for in situ measurement of drug target engagement and cell signaling pathways

Nathan McMahon, Allison Solanki, Jocelyn Jones, Sunjong Kwon, Young Hwan Chang, Koei Chin, Michel Nederlof, Joe Gray, Summer L. Gibbs

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Successful targeted cancer treatment continues to elude modern medicine and its many therapeutic strategies. Herein, we propose a fluorescent imaging technique to measure drug localization and subsequent cell signaling perturbations on a single cell basis.

Original languageEnglish (US)
Title of host publicationMicroscopy Histopathology and Analytics, Microscopy 2020
PublisherOSA - The Optical Society
ISBN (Electronic)9781557528209
DOIs
StatePublished - 2020
EventMicroscopy Histopathology and Analytics, Microscopy 2020 - Washington, United States
Duration: Apr 20 2020Apr 23 2020

Publication series

NameOptics InfoBase Conference Papers
VolumePart F177-Microscopy-2020

Conference

ConferenceMicroscopy Histopathology and Analytics, Microscopy 2020
CountryUnited States
City Washington
Period4/20/204/23/20

ASJC Scopus subject areas

  • Mechanics of Materials
  • Electronic, Optical and Magnetic Materials

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