Fixed-apex Mitral Annular Descent Correlates Better with Left Ventricular Systolic Function than Does Free-apex Left Ventricular Long-axis Shortening

Filiberto Rodriguez, Frederick (Fred) Tibayan, Julie R. Glasson, David Liang, George T. Daughters, Neil B. Ingels, D. Craig Miller

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Echocardiographic measures of mitral annular descent (MAD) assume a fixed left ventricular (LV) apex throughout the cardiac cycle, ignoring the apical component of LV long-axis shortening (LAS). We tested whether apical motion contributes significantly to LAS, making LAS a better surrogate of LV systolic function than MAD. Three-dimensional LV systolic MAD, LAS, and apical motion were measured in sheep using implanted radiopaque markers and biplane videofluoroscopy. End-diastolic volume-stroke work relationship (preload recruitable stroke work) was computed as a load-independent index of LV systolic function. Apical motion was 1.4 ± 0.8 mm, representing 22% of LAS (P <.05). Linear regression demonstrated that MAD correlated slightly better with preload recruitable stroke work (r = 0.808) than LAS (r = 0.792, both P <.001). Receiver operating characteristic curves demonstrated MAD was more accurate in predicting depressed LV function than LAS (93% vs 84%, respectively). Although LV apical motion contributed significantly to LAS, MAD measured with a fixed-apex assumption, as currently done echocardiographically, correlated more closely with LV preload recruitable stroke work.

Original languageEnglish (US)
Pages (from-to)101-107
Number of pages7
JournalJournal of the American Society of Echocardiography
Volume17
Issue number2
DOIs
StatePublished - Feb 2004
Externally publishedYes

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Left Ventricular Function
Stroke
ROC Curve
Stroke Volume
Linear Models
Sheep

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Fixed-apex Mitral Annular Descent Correlates Better with Left Ventricular Systolic Function than Does Free-apex Left Ventricular Long-axis Shortening. / Rodriguez, Filiberto; Tibayan, Frederick (Fred); Glasson, Julie R.; Liang, David; Daughters, George T.; Ingels, Neil B.; Miller, D. Craig.

In: Journal of the American Society of Echocardiography, Vol. 17, No. 2, 02.2004, p. 101-107.

Research output: Contribution to journalArticle

Rodriguez, Filiberto ; Tibayan, Frederick (Fred) ; Glasson, Julie R. ; Liang, David ; Daughters, George T. ; Ingels, Neil B. ; Miller, D. Craig. / Fixed-apex Mitral Annular Descent Correlates Better with Left Ventricular Systolic Function than Does Free-apex Left Ventricular Long-axis Shortening. In: Journal of the American Society of Echocardiography. 2004 ; Vol. 17, No. 2. pp. 101-107.
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