Fivefold higher rate of pseudarthrosis with polyetheretherketone interbody device than with structural allograft used for 1-level anterior cervical discectomy and fusion

Katie L. Krause, James T. Obayashi, Kelly J. Bridges, Ahmed Raslan, Khoi Than

Research output: Contribution to journalArticle

2 Scopus citations


In BriefThe authors examined fusion rates after single-level anterior cervical discectomy and fusion, comparing use of a structural allograft with use of polyetheretherketone (PEEK) interbody devices packed with bone graft. The results demonstrate superior results of structural allograft in terms of arthrodesis rates and reoperation rates. Currently, reimbursement rates substantially favor the use of PEEK and other synthetic devices, which the authors believe should be changed based on the results of this study.

Original languageEnglish (US)
Pages (from-to)46-51
Number of pages6
JournalJournal of neurosurgery. Spine
Issue number1
Publication statusPublished - Oct 30 2018



  • ACDF
  • ACDF = anterior cervical discectomy and fusion
  • allograft
  • anterior cervical discectomy and fusion
  • DBM = demineralized bone matrix
  • PEEK
  • PEEK = polyetheretherketone
  • pseudarthrosis
  • QALY = quality-adjusted life-year
  • rhBMP-2 = recombinant human bone morphogenetic protein–2

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology

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