Abstract
In this issue, Häberlein et al. demonstrate a role for GPR17 in regulating zebrafish oligodendrocyte differentiation. Zebrafish expressing a humanized GPR17 respond to modulators, which are inactive against the endogenous zebrafish receptor. These findings highlight the potential for humanized zebrafish as an in vivo platform for targeted remyelination drug screens.
Original language | English (US) |
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Pages (from-to) | 1467-1469 |
Number of pages | 3 |
Journal | Cell Chemical Biology |
Volume | 29 |
Issue number | 10 |
DOIs |
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State | Published - Oct 20 2022 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmacology
- Drug Discovery
- Clinical Biochemistry