First Episode and Recurrent Venous Thromboembolism: Who is Identifiably at Risk?

    Research output: Contribution to journalArticle

    9 Citations (Scopus)

    Abstract

    Management of venous thromboembolism (VTE) has undergone a significant evolution in the past two decades. Two of the more common heritable thrombophilias were identified (Factor V Leiden and prothrombin 20210A gene mutation) in the early to mid-1990s. These and other inherited and acquired hypercoagulable conditions were found to place patients at higher risk for developing a first episode of VTE. However, their roles in development of recurrent VTE remain uncertain. More recently, other clinical risk factors that are associated with increased risk for VTE have been identified. This information has allowed physicians to stratify the type and duration of anticoagulation based not only on the presence of thrombophilias, but also on other clinical characteristics that increase risk for a first episode of and recurrent VTE.

    Original languageEnglish (US)
    Pages (from-to)132-138
    Number of pages7
    JournalSeminars in Vascular Surgery
    Volume21
    Issue number3
    DOIs
    StatePublished - Sep 2008

    Fingerprint

    Venous Thromboembolism
    Prothrombin
    Physicians
    Mutation
    Genes

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine

    Cite this

    First Episode and Recurrent Venous Thromboembolism : Who is Identifiably at Risk? / Liem, Timothy; Deloughery, Thomas.

    In: Seminars in Vascular Surgery, Vol. 21, No. 3, 09.2008, p. 132-138.

    Research output: Contribution to journalArticle

    @article{ddf1286d1673437eb4b910ceb9efcdf9,
    title = "First Episode and Recurrent Venous Thromboembolism: Who is Identifiably at Risk?",
    abstract = "Management of venous thromboembolism (VTE) has undergone a significant evolution in the past two decades. Two of the more common heritable thrombophilias were identified (Factor V Leiden and prothrombin 20210A gene mutation) in the early to mid-1990s. These and other inherited and acquired hypercoagulable conditions were found to place patients at higher risk for developing a first episode of VTE. However, their roles in development of recurrent VTE remain uncertain. More recently, other clinical risk factors that are associated with increased risk for VTE have been identified. This information has allowed physicians to stratify the type and duration of anticoagulation based not only on the presence of thrombophilias, but also on other clinical characteristics that increase risk for a first episode of and recurrent VTE.",
    author = "Timothy Liem and Thomas Deloughery",
    year = "2008",
    month = "9",
    doi = "10.1053/j.semvascsurg.2008.05.006",
    language = "English (US)",
    volume = "21",
    pages = "132--138",
    journal = "Seminars in Vascular Surgery",
    issn = "0895-7967",
    publisher = "W.B. Saunders Ltd",
    number = "3",

    }

    TY - JOUR

    T1 - First Episode and Recurrent Venous Thromboembolism

    T2 - Who is Identifiably at Risk?

    AU - Liem, Timothy

    AU - Deloughery, Thomas

    PY - 2008/9

    Y1 - 2008/9

    N2 - Management of venous thromboembolism (VTE) has undergone a significant evolution in the past two decades. Two of the more common heritable thrombophilias were identified (Factor V Leiden and prothrombin 20210A gene mutation) in the early to mid-1990s. These and other inherited and acquired hypercoagulable conditions were found to place patients at higher risk for developing a first episode of VTE. However, their roles in development of recurrent VTE remain uncertain. More recently, other clinical risk factors that are associated with increased risk for VTE have been identified. This information has allowed physicians to stratify the type and duration of anticoagulation based not only on the presence of thrombophilias, but also on other clinical characteristics that increase risk for a first episode of and recurrent VTE.

    AB - Management of venous thromboembolism (VTE) has undergone a significant evolution in the past two decades. Two of the more common heritable thrombophilias were identified (Factor V Leiden and prothrombin 20210A gene mutation) in the early to mid-1990s. These and other inherited and acquired hypercoagulable conditions were found to place patients at higher risk for developing a first episode of VTE. However, their roles in development of recurrent VTE remain uncertain. More recently, other clinical risk factors that are associated with increased risk for VTE have been identified. This information has allowed physicians to stratify the type and duration of anticoagulation based not only on the presence of thrombophilias, but also on other clinical characteristics that increase risk for a first episode of and recurrent VTE.

    UR - http://www.scopus.com/inward/record.url?scp=50949090336&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=50949090336&partnerID=8YFLogxK

    U2 - 10.1053/j.semvascsurg.2008.05.006

    DO - 10.1053/j.semvascsurg.2008.05.006

    M3 - Article

    C2 - 18774448

    AN - SCOPUS:50949090336

    VL - 21

    SP - 132

    EP - 138

    JO - Seminars in Vascular Surgery

    JF - Seminars in Vascular Surgery

    SN - 0895-7967

    IS - 3

    ER -