Finite element analysis of temperature controlled coagulation in laser irradiated tissue

Tami N. Glenn, Sohi Rastegar, Steven Jacques

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The Theoretical study of thermal damage processes in laser irradiated tissue provides further insight into the design of optimal coagulation procedures. Controlled laser coagulation of tissue was studied theoretically using a finite element method with a modulating laser heat source to simulate feedback controlled laser delivery with a constant surface temperature. The effects of uncertainty in scattering and absorption properties of the tissue, thermal denaturation induced changes in optical properties, and surface convection were analyzed. Compared to a single pulse CW irradiation in which a doctor would presumably stop CW laser delivery after noticing some effect such as vaporization or carbonization, the constant surface temperature scenario provided a better overall control over the coagulation process. In particular, prediction of coagulative damage in a constant temperature scenario was less sensitive to uncertainties in optical properties and their dynamic changes during the course of coagulation. Also, subsurface overheating under surface convective conditions could be compensated for under constant temperature irradiation by lowering the surface temperature.

Original languageEnglish (US)
Pages (from-to)79-87
Number of pages9
JournalIEEE Transactions on Biomedical Engineering
Volume43
Issue number1
DOIs
StatePublished - Jan 1996
Externally publishedYes

Fingerprint

Coagulation
Tissue
Finite element method
Lasers
Temperature
Optical properties
Irradiation
Denaturation
Continuous wave lasers
Carbonization
Vaporization
Light sources
Scattering
Feedback
Hot Temperature
Uncertainty

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Finite element analysis of temperature controlled coagulation in laser irradiated tissue. / Glenn, Tami N.; Rastegar, Sohi; Jacques, Steven.

In: IEEE Transactions on Biomedical Engineering, Vol. 43, No. 1, 01.1996, p. 79-87.

Research output: Contribution to journalArticle

Glenn, Tami N. ; Rastegar, Sohi ; Jacques, Steven. / Finite element analysis of temperature controlled coagulation in laser irradiated tissue. In: IEEE Transactions on Biomedical Engineering. 1996 ; Vol. 43, No. 1. pp. 79-87.
@article{abc5162d5f3d4e11b5dbfbe4cc8c287d,
title = "Finite element analysis of temperature controlled coagulation in laser irradiated tissue",
abstract = "The Theoretical study of thermal damage processes in laser irradiated tissue provides further insight into the design of optimal coagulation procedures. Controlled laser coagulation of tissue was studied theoretically using a finite element method with a modulating laser heat source to simulate feedback controlled laser delivery with a constant surface temperature. The effects of uncertainty in scattering and absorption properties of the tissue, thermal denaturation induced changes in optical properties, and surface convection were analyzed. Compared to a single pulse CW irradiation in which a doctor would presumably stop CW laser delivery after noticing some effect such as vaporization or carbonization, the constant surface temperature scenario provided a better overall control over the coagulation process. In particular, prediction of coagulative damage in a constant temperature scenario was less sensitive to uncertainties in optical properties and their dynamic changes during the course of coagulation. Also, subsurface overheating under surface convective conditions could be compensated for under constant temperature irradiation by lowering the surface temperature.",
author = "Glenn, {Tami N.} and Sohi Rastegar and Steven Jacques",
year = "1996",
month = "1",
doi = "10.1109/10.477703",
language = "English (US)",
volume = "43",
pages = "79--87",
journal = "IEEE Transactions on Biomedical Engineering",
issn = "0018-9294",
publisher = "IEEE Computer Society",
number = "1",

}

TY - JOUR

T1 - Finite element analysis of temperature controlled coagulation in laser irradiated tissue

AU - Glenn, Tami N.

AU - Rastegar, Sohi

AU - Jacques, Steven

PY - 1996/1

Y1 - 1996/1

N2 - The Theoretical study of thermal damage processes in laser irradiated tissue provides further insight into the design of optimal coagulation procedures. Controlled laser coagulation of tissue was studied theoretically using a finite element method with a modulating laser heat source to simulate feedback controlled laser delivery with a constant surface temperature. The effects of uncertainty in scattering and absorption properties of the tissue, thermal denaturation induced changes in optical properties, and surface convection were analyzed. Compared to a single pulse CW irradiation in which a doctor would presumably stop CW laser delivery after noticing some effect such as vaporization or carbonization, the constant surface temperature scenario provided a better overall control over the coagulation process. In particular, prediction of coagulative damage in a constant temperature scenario was less sensitive to uncertainties in optical properties and their dynamic changes during the course of coagulation. Also, subsurface overheating under surface convective conditions could be compensated for under constant temperature irradiation by lowering the surface temperature.

AB - The Theoretical study of thermal damage processes in laser irradiated tissue provides further insight into the design of optimal coagulation procedures. Controlled laser coagulation of tissue was studied theoretically using a finite element method with a modulating laser heat source to simulate feedback controlled laser delivery with a constant surface temperature. The effects of uncertainty in scattering and absorption properties of the tissue, thermal denaturation induced changes in optical properties, and surface convection were analyzed. Compared to a single pulse CW irradiation in which a doctor would presumably stop CW laser delivery after noticing some effect such as vaporization or carbonization, the constant surface temperature scenario provided a better overall control over the coagulation process. In particular, prediction of coagulative damage in a constant temperature scenario was less sensitive to uncertainties in optical properties and their dynamic changes during the course of coagulation. Also, subsurface overheating under surface convective conditions could be compensated for under constant temperature irradiation by lowering the surface temperature.

UR - http://www.scopus.com/inward/record.url?scp=0030049874&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030049874&partnerID=8YFLogxK

U2 - 10.1109/10.477703

DO - 10.1109/10.477703

M3 - Article

VL - 43

SP - 79

EP - 87

JO - IEEE Transactions on Biomedical Engineering

JF - IEEE Transactions on Biomedical Engineering

SN - 0018-9294

IS - 1

ER -