Finite-difference modeling of laser ablation of tissue

Steven Jacques

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Citations (Scopus)

Abstract

Finite-difference modeling offers a flexible approach toward modeling tissue ablation. The model presented here considers optical penetration of the laser, thermal diffusion, water diffusion, surface evaporation, carbonization, and subsurface explosive vaporization. An example simulation considers near-infrared diode laser heating and ablation of a low-absorption nonscattering tissue which has been superficially stained with an absorbing dye (indocyanine green, ICG). Computer simulation illustrates 5 distinct phases of the process: (1) initial heating due to ICG absorption, (2) evaporation with surface clamped at 100°C which desiccates surface layer, (3) heating of surface after desiccation has slowed evaporation, (4) rapid heating after onset of carbonization due to combination of desiccation and heating, and (5) subsurface explosive vaporization which removes a superficial tissue layer and exposes a fresh surface which repeats the above cycle.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Society of Photo-Optical Instrumentation Engineers
Pages422-431
Number of pages10
Volume1882
ISBN (Print)0819411094
StatePublished - 1993
Externally publishedYes
EventLaser-Tissue Interaction IV - Los Angeles, CA, USA
Duration: Jan 18 1993Jan 20 1993

Other

OtherLaser-Tissue Interaction IV
CityLos Angeles, CA, USA
Period1/18/931/20/93

Fingerprint

Laser ablation
laser ablation
Tissue
Heating
Evaporation
heating
carbonization
Carbonization
evaporation
Vaporization
drying
Laser heating
Thermal diffusion
Surface diffusion
laser heating
thermal diffusion
surface diffusion
Ablation
ablation
Semiconductor lasers

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Jacques, S. (1993). Finite-difference modeling of laser ablation of tissue. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 1882, pp. 422-431). Publ by Society of Photo-Optical Instrumentation Engineers.

Finite-difference modeling of laser ablation of tissue. / Jacques, Steven.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1882 Publ by Society of Photo-Optical Instrumentation Engineers, 1993. p. 422-431.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jacques, S 1993, Finite-difference modeling of laser ablation of tissue. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 1882, Publ by Society of Photo-Optical Instrumentation Engineers, pp. 422-431, Laser-Tissue Interaction IV, Los Angeles, CA, USA, 1/18/93.
Jacques S. Finite-difference modeling of laser ablation of tissue. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1882. Publ by Society of Photo-Optical Instrumentation Engineers. 1993. p. 422-431
Jacques, Steven. / Finite-difference modeling of laser ablation of tissue. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1882 Publ by Society of Photo-Optical Instrumentation Engineers, 1993. pp. 422-431
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