Finite-difference modeling of laser ablation of tissue

Steven L. Jacques

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Scopus citations

Abstract

Finite-difference modeling offers a flexible approach toward modeling tissue ablation. The model presented here considers optical penetration of the laser, thermal diffusion, water diffusion, surface evaporation, carbonization, and subsurface explosive vaporization. An example simulation considers near-infrared diode laser heating and ablation of a low-absorption nonscattering tissue which has been superficially stained with an absorbing dye (indocyanine green, ICG). Computer simulation illustrates 5 distinct phases of the process: (1) initial heating due to ICG absorption, (2) evaporation with surface clamped at 100°C which desiccates surface layer, (3) heating of surface after desiccation has slowed evaporation, (4) rapid heating after onset of carbonization due to combination of desiccation and heating, and (5) subsurface explosive vaporization which removes a superficial tissue layer and exposes a fresh surface which repeats the above cycle.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Society of Photo-Optical Instrumentation Engineers
Pages422-431
Number of pages10
ISBN (Print)0819411094, 9780819411099
DOIs
StatePublished - 1993
Externally publishedYes
EventLaser-Tissue Interaction IV - Los Angeles, CA, USA
Duration: Jan 18 1993Jan 20 1993

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1882
ISSN (Print)0277-786X

Other

OtherLaser-Tissue Interaction IV
CityLos Angeles, CA, USA
Period1/18/931/20/93

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Jacques, S. L. (1993). Finite-difference modeling of laser ablation of tissue. In Proceedings of SPIE - The International Society for Optical Engineering (pp. 422-431). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1882). Publ by Society of Photo-Optical Instrumentation Engineers. https://doi.org/10.1117/12.147688