TY - JOUR
T1 - Financial Toxicity after Acute Respiratory Distress Syndrome
T2 - A National Qualitative Cohort Study∗
AU - Hauschildt, Katrina E.
AU - Seigworth, Claire
AU - Kamphuis, Lee A.
AU - Hough, Catherine L.
AU - Moss, Marc
AU - McPeake, Joanne M.
AU - Iwashyna, Theodore J.
N1 - Funding Information:
Drs. Iwashyna and Hough, Ms. Kamphuis, and Dr. Moss conceived of and designed the study. Drs. Hough, Moss, and Iwashyna obtained funding. Ms. Hauschildt conducted the interviews with assistance from Ms. Seigworth and Ms. Kamphuis. Ms. Hauschildt, Ms. Seigworth, and Drs. Hough and Iwashyna conducted the data analysis. Ms. Hauschildt drafted the initial article. All authors conducted critical revision of the article for important intellectual content and approved the final version of the article. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/ ccmjournal). Supported, in part, by grants U01 HL123031 and R01 HL132232 from the National Institutes of Health. Ms. Hauschildt, Ms. Kamphuis, and Drs. Hough and Iwashyna received support for article research from the National Institutes of Health. Ms. Kamphuis’ and Dr. Hough’s institutions received funding from the National Heart, Lung, and Blood Institute. Ms. Kamphuis and Dr. Iwashyna disclosed government work. Dr. McPeake’s institution received funding from Society of Critical Care Medicine and the Health Foundation. The remaining authors have disclosed that they do not have any potential conflicts of interest.
Publisher Copyright:
© 2020 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Objectives: The financial burdens and subsequent related distress of medical care, referred to as financial toxicity, may limit access to beneficial treatments. However, financial toxicity after acute care is less described- A nd may be an important but underexplored mechanism preventing full recovery after critical illnesses such as acute respiratory distress syndrome. We sought to identify the mechanisms by which financial toxicity manifested in patients with acute respiratory distress syndrome, protective factors against such toxicity, and the consequences of financial toxicity to survivors' lives following acute respiratory distress syndrome. Design: We conducted semistructured interviews following patients' hospitalization and during recovery as an ancillary study to a multicenter randomized clinical trial in acute respiratory distress syndrome. Patients were 9-16 months post randomization at the time of interview. Setting and Participants: The Reevaluation Of Systemic Early Neuromuscular Blockade trial examined the use of early neuromuscular blockade in mechanically ventilated patients with moderate/severe acute respiratory distress syndrome. We recruited consecutive surviving patients who were English speaking, consented to follow-up, and were randomized between December 11, 2017, and May 4, 2018 (n = 79) from 29 U.S. sites. Measurements and Main Results: We asked about patients' perceptions of financial burden(s) that they associated with their acute respiratory distress syndrome hospitalization. Forty-six of 79 eligible acute respiratory distress syndrome survivors (58%) participated (from 22 sites); their median age was 56 (interquartile range 47-62). Thirty-one of 46 reported at least one acute respiratory distress syndrome-related financial impact. Financial toxicity manifested via medical bills, changes in insurance coverage, and loss of employment income. Respondents reported not working prior to acute respiratory distress syndrome, using Medicaid or Medicare, or, conversely, generous work benefits as factors which may have limited financial burdens. Patients reported multiple consequences of acute respiratory distress syndrome-related financial toxicity, including harms to their mental and physical health, increased reliance on others, and specific material hardships. Conclusions: Financial toxicity related to critical illness is common and may limit patients' emotional, physical, and social recovery after acute respiratory distress syndrome hospitalization for at least a year.
AB - Objectives: The financial burdens and subsequent related distress of medical care, referred to as financial toxicity, may limit access to beneficial treatments. However, financial toxicity after acute care is less described- A nd may be an important but underexplored mechanism preventing full recovery after critical illnesses such as acute respiratory distress syndrome. We sought to identify the mechanisms by which financial toxicity manifested in patients with acute respiratory distress syndrome, protective factors against such toxicity, and the consequences of financial toxicity to survivors' lives following acute respiratory distress syndrome. Design: We conducted semistructured interviews following patients' hospitalization and during recovery as an ancillary study to a multicenter randomized clinical trial in acute respiratory distress syndrome. Patients were 9-16 months post randomization at the time of interview. Setting and Participants: The Reevaluation Of Systemic Early Neuromuscular Blockade trial examined the use of early neuromuscular blockade in mechanically ventilated patients with moderate/severe acute respiratory distress syndrome. We recruited consecutive surviving patients who were English speaking, consented to follow-up, and were randomized between December 11, 2017, and May 4, 2018 (n = 79) from 29 U.S. sites. Measurements and Main Results: We asked about patients' perceptions of financial burden(s) that they associated with their acute respiratory distress syndrome hospitalization. Forty-six of 79 eligible acute respiratory distress syndrome survivors (58%) participated (from 22 sites); their median age was 56 (interquartile range 47-62). Thirty-one of 46 reported at least one acute respiratory distress syndrome-related financial impact. Financial toxicity manifested via medical bills, changes in insurance coverage, and loss of employment income. Respondents reported not working prior to acute respiratory distress syndrome, using Medicaid or Medicare, or, conversely, generous work benefits as factors which may have limited financial burdens. Patients reported multiple consequences of acute respiratory distress syndrome-related financial toxicity, including harms to their mental and physical health, increased reliance on others, and specific material hardships. Conclusions: Financial toxicity related to critical illness is common and may limit patients' emotional, physical, and social recovery after acute respiratory distress syndrome hospitalization for at least a year.
KW - Medicaid
KW - cost of illness
KW - health status disparities
KW - insurance
KW - quality of life
KW - social determinants of health
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UR - http://www.scopus.com/inward/citedby.url?scp=85088458200&partnerID=8YFLogxK
U2 - 10.1097/CCM.0000000000004378
DO - 10.1097/CCM.0000000000004378
M3 - Article
C2 - 32392019
AN - SCOPUS:85088458200
VL - 48
SP - 1103
EP - 1110
JO - Critical Care Medicine
JF - Critical Care Medicine
SN - 0090-3493
IS - 8
ER -