Fibromyalgia and the facts: Sense or nonsense

R. M. Bennett

    Research output: Contribution to journalReview articlepeer-review

    53 Scopus citations


    A recent flurry of important studies has provided critical new information that is relevant to the contemporary understanding of the fibromyalgia syndrome. The concept that these patients represent solely a form of masked depression or a distinctive syndrome of somatization is not supported by the current facts. Rather it would appear that a characteristic peripheral nociceptive component is modulated by an interplay of complex central factors. A disruption of the neuroendocrine axis controlling growth hormone production may be the link between disturbed sleep and muscle pain, as growth hormone is produced predominantly during stage four sleep. A paradigm to link some of these newer findings is presented.

    Original languageEnglish (US)
    Pages (from-to)45-59
    Number of pages15
    JournalRheumatic Disease Clinics of North America
    Issue number1
    StatePublished - Jan 1 1993

    ASJC Scopus subject areas

    • Rheumatology


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