Fibrin glue augmentation for flexor tendon repair increases friction compared with epitendinous suture

N. Michael Xu, Philip J. Brown, Johannes F. Plate, Omar Nazir, George S. Gluck, Joel D. Stitzel, Zhongyu Li

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose To compare the gliding resistance, repair gapping, and ultimate strength of a common suture construct with a modified construct with fibrin glue augmentation. Methods Twelve human cadaveric flexor digitorum profundus tendons were transected and repaired with a 4-strand core suture. Specimens were divided into 2 groups and augmented with epitendinous suture (n = 6) or fibrin glue (n = 6). We compared gliding resistance, 2-mm gapping, and ultimate strength of the repaired tendon between groups. Results The linear stiffness, force to produce a 2-mm gap, and ultimate failure were similar in both repair methods. However, the 4-strand suture repair with fibrin glue augmentation displayed significantly higher gliding resistance compared with the 4-strand suture with a running epitendinous suture. Conclusions The significantly increased gliding resistance associated with fibrin glue raises questions regarding the use of this material for flexor tendon repair augmentation. Clinical relevance In a human cadaveric study, fibrin glue augmentation to zone II flexor tendon repairs significantly increased friction in the tendon sheath compared with an epitendinous suture.

Original languageEnglish (US)
Pages (from-to)2329-2334
Number of pages6
JournalJournal of Hand Surgery
Volume38
Issue number12
DOIs
StatePublished - Dec 2013
Externally publishedYes

Fingerprint

Fibrin Tissue Adhesive
Friction
Tendons
Sutures
Running

Keywords

  • Biomechanics
  • gliding resistance
  • repair gapping
  • repair strength
  • zone II repair

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Fibrin glue augmentation for flexor tendon repair increases friction compared with epitendinous suture. / Xu, N. Michael; Brown, Philip J.; Plate, Johannes F.; Nazir, Omar; Gluck, George S.; Stitzel, Joel D.; Li, Zhongyu.

In: Journal of Hand Surgery, Vol. 38, No. 12, 12.2013, p. 2329-2334.

Research output: Contribution to journalArticle

Xu, N. Michael ; Brown, Philip J. ; Plate, Johannes F. ; Nazir, Omar ; Gluck, George S. ; Stitzel, Joel D. ; Li, Zhongyu. / Fibrin glue augmentation for flexor tendon repair increases friction compared with epitendinous suture. In: Journal of Hand Surgery. 2013 ; Vol. 38, No. 12. pp. 2329-2334.
@article{d7889af055444b6b97c51580bd1dc3cf,
title = "Fibrin glue augmentation for flexor tendon repair increases friction compared with epitendinous suture",
abstract = "Purpose To compare the gliding resistance, repair gapping, and ultimate strength of a common suture construct with a modified construct with fibrin glue augmentation. Methods Twelve human cadaveric flexor digitorum profundus tendons were transected and repaired with a 4-strand core suture. Specimens were divided into 2 groups and augmented with epitendinous suture (n = 6) or fibrin glue (n = 6). We compared gliding resistance, 2-mm gapping, and ultimate strength of the repaired tendon between groups. Results The linear stiffness, force to produce a 2-mm gap, and ultimate failure were similar in both repair methods. However, the 4-strand suture repair with fibrin glue augmentation displayed significantly higher gliding resistance compared with the 4-strand suture with a running epitendinous suture. Conclusions The significantly increased gliding resistance associated with fibrin glue raises questions regarding the use of this material for flexor tendon repair augmentation. Clinical relevance In a human cadaveric study, fibrin glue augmentation to zone II flexor tendon repairs significantly increased friction in the tendon sheath compared with an epitendinous suture.",
keywords = "Biomechanics, gliding resistance, repair gapping, repair strength, zone II repair",
author = "Xu, {N. Michael} and Brown, {Philip J.} and Plate, {Johannes F.} and Omar Nazir and Gluck, {George S.} and Stitzel, {Joel D.} and Zhongyu Li",
year = "2013",
month = "12",
doi = "10.1016/j.jhsa.2013.09.007",
language = "English (US)",
volume = "38",
pages = "2329--2334",
journal = "Journal of Hand Surgery",
issn = "0363-5023",
publisher = "W.B. Saunders Ltd",
number = "12",

}

TY - JOUR

T1 - Fibrin glue augmentation for flexor tendon repair increases friction compared with epitendinous suture

AU - Xu, N. Michael

AU - Brown, Philip J.

AU - Plate, Johannes F.

AU - Nazir, Omar

AU - Gluck, George S.

AU - Stitzel, Joel D.

AU - Li, Zhongyu

PY - 2013/12

Y1 - 2013/12

N2 - Purpose To compare the gliding resistance, repair gapping, and ultimate strength of a common suture construct with a modified construct with fibrin glue augmentation. Methods Twelve human cadaveric flexor digitorum profundus tendons were transected and repaired with a 4-strand core suture. Specimens were divided into 2 groups and augmented with epitendinous suture (n = 6) or fibrin glue (n = 6). We compared gliding resistance, 2-mm gapping, and ultimate strength of the repaired tendon between groups. Results The linear stiffness, force to produce a 2-mm gap, and ultimate failure were similar in both repair methods. However, the 4-strand suture repair with fibrin glue augmentation displayed significantly higher gliding resistance compared with the 4-strand suture with a running epitendinous suture. Conclusions The significantly increased gliding resistance associated with fibrin glue raises questions regarding the use of this material for flexor tendon repair augmentation. Clinical relevance In a human cadaveric study, fibrin glue augmentation to zone II flexor tendon repairs significantly increased friction in the tendon sheath compared with an epitendinous suture.

AB - Purpose To compare the gliding resistance, repair gapping, and ultimate strength of a common suture construct with a modified construct with fibrin glue augmentation. Methods Twelve human cadaveric flexor digitorum profundus tendons were transected and repaired with a 4-strand core suture. Specimens were divided into 2 groups and augmented with epitendinous suture (n = 6) or fibrin glue (n = 6). We compared gliding resistance, 2-mm gapping, and ultimate strength of the repaired tendon between groups. Results The linear stiffness, force to produce a 2-mm gap, and ultimate failure were similar in both repair methods. However, the 4-strand suture repair with fibrin glue augmentation displayed significantly higher gliding resistance compared with the 4-strand suture with a running epitendinous suture. Conclusions The significantly increased gliding resistance associated with fibrin glue raises questions regarding the use of this material for flexor tendon repair augmentation. Clinical relevance In a human cadaveric study, fibrin glue augmentation to zone II flexor tendon repairs significantly increased friction in the tendon sheath compared with an epitendinous suture.

KW - Biomechanics

KW - gliding resistance

KW - repair gapping

KW - repair strength

KW - zone II repair

UR - http://www.scopus.com/inward/record.url?scp=84888434263&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84888434263&partnerID=8YFLogxK

U2 - 10.1016/j.jhsa.2013.09.007

DO - 10.1016/j.jhsa.2013.09.007

M3 - Article

C2 - 24275055

AN - SCOPUS:84888434263

VL - 38

SP - 2329

EP - 2334

JO - Journal of Hand Surgery

JF - Journal of Hand Surgery

SN - 0363-5023

IS - 12

ER -