Fiber-based microendoscopic multiphoton imaging

Gangjun Liu, Khanh Kieu, Frank W. Wise, Brian Wong, Zhongping Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We developed a multiphoton microscope which integrates an all normal dispersion fiber laser, a double cladding photonic crystal fiber and a MEMS mirror scanner based hand-held probe. The fiber laser has a central wavelength of 1.06μm,a repetition rate of 76MHz and maximum average output power of more than 1W. The MEMS mirror based probe is compact and Second harmonic generation and two photon excited fluorescence images of biological sample were demonstrated.

Original languageEnglish (US)
Title of host publicationPhotonic Therapeutics and Diagnostics VI
DOIs
StatePublished - 2010
EventPhotonic Therapeutics and Diagnostics VI - San Francisco, CA, United States
Duration: Jan 23 2010Jan 25 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7548
ISSN (Print)1605-7422

Other

OtherPhotonic Therapeutics and Diagnostics VI
CountryUnited States
CitySan Francisco, CA
Period1/23/101/25/10

Keywords

  • Endoscope
  • Multiphoton microscope
  • Photonic crystal fiber
  • Ultrafast fiber laser

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Liu, G., Kieu, K., Wise, F. W., Wong, B., & Chen, Z. (2010). Fiber-based microendoscopic multiphoton imaging. In Photonic Therapeutics and Diagnostics VI [754829] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7548). https://doi.org/10.1117/12.850792