Fiber-based microendoscopic multiphoton imaging

Gangjun Liu, Khanh Kieu, Frank W. Wise, Brian Wong, Zhongping Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We developed a multiphoton microscope which integrates an all normal dispersion fiber laser, a double cladding photonic crystal fiber and a MEMS mirror scanner based hand-held probe. The fiber laser has a central wavelength of 1.06μm,a repetition rate of 76MHz and maximum average output power of more than 1W. The MEMS mirror based probe is compact and Second harmonic generation and two photon excited fluorescence images of biological sample were demonstrated.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7548
DOIs
StatePublished - 2010
Externally publishedYes
EventPhotonic Therapeutics and Diagnostics VI - San Francisco, CA, United States
Duration: Jan 23 2010Jan 25 2010

Other

OtherPhotonic Therapeutics and Diagnostics VI
CountryUnited States
CitySan Francisco, CA
Period1/23/101/25/10

Fingerprint

Micro-Electrical-Mechanical Systems
Fiber lasers
microelectromechanical systems
MEMS
fiber lasers
Mirrors
Lasers
Optics and Photonics
mirrors
Imaging techniques
fibers
Photonic crystal fibers
Fibers
probes
Harmonic generation
Photons
scanners
repetition
harmonic generations
Microscopes

Keywords

  • Endoscope
  • Multiphoton microscope
  • Photonic crystal fiber
  • Ultrafast fiber laser

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Liu, G., Kieu, K., Wise, F. W., Wong, B., & Chen, Z. (2010). Fiber-based microendoscopic multiphoton imaging. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7548). [754829] https://doi.org/10.1117/12.850792

Fiber-based microendoscopic multiphoton imaging. / Liu, Gangjun; Kieu, Khanh; Wise, Frank W.; Wong, Brian; Chen, Zhongping.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7548 2010. 754829.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Liu, G, Kieu, K, Wise, FW, Wong, B & Chen, Z 2010, Fiber-based microendoscopic multiphoton imaging. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7548, 754829, Photonic Therapeutics and Diagnostics VI, San Francisco, CA, United States, 1/23/10. https://doi.org/10.1117/12.850792
Liu G, Kieu K, Wise FW, Wong B, Chen Z. Fiber-based microendoscopic multiphoton imaging. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7548. 2010. 754829 https://doi.org/10.1117/12.850792
Liu, Gangjun ; Kieu, Khanh ; Wise, Frank W. ; Wong, Brian ; Chen, Zhongping. / Fiber-based microendoscopic multiphoton imaging. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7548 2010.
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