@inproceedings{5f9d8570653547738d01d387fcc52373,
title = "Fiber-based combined optical coherence and multiphoton microscopy",
abstract = "This manuscript demonstrates a multimodal imaging system which combined multiphoton microscopy (MPM) imaging modality with Fourier domain (FD) optical coherence microscopy (OCM) imaging modality. The system used a single fiber-based femtosecond laser as the light source for both MPM and OCM modality. The femtosecond fiber laser has a central wavlength of 1.03 μm, a pulse width of 120 fs and a bandwidth of 29 nm. The systems used fiber-based devices for both MPM and OCM imaging. The MPM and OCM shared the same excitation light path. The excitation light was delivered with the core of a dual-clad fiber. The MPM and OCM signal was collected by different parts of the dual-clad fiber. The MPM signal was collected by the clad of the dual-clad fiber and the OCM signal was collected by the core of the dual-clad fiber. The FD OCM used a home-built InGaAs detector array spectrometer with a maximum Aline speed of 7.7 KHz. The multiphoton signal collection efficiency was analyzed and several imaging modality including second harmonic generation imaging, two-photon excited fluorescence and optical coherent microscopy imaging were demonstrated.",
keywords = "multimodal imaging, multiphoton microscopy, nonlinear laser scanning microscopy, optical coherence microscopy",
author = "Gangjun Liu and Zhongping Chen",
year = "2011",
month = may,
day = "2",
doi = "10.1117/12.874267",
language = "English (US)",
isbn = "9780819484291",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Multimodal Biomedical Imaging VI",
note = "Multimodal Biomedical Imaging VI ; Conference date: 22-01-2011 Through 23-01-2011",
}