This paper describes the first animal model of a virally induced uveal melanoma. Tumors developed following the injection of an RNA tumor virus, i.e., Gardner strain feline sarcoma virus, into the anterior chamber of newborn kitterns. Histogically, the tumors were found to be iris and ciliary body melanomas, many of which showed invasion. The histology and ultrastructure of those tumors are described.
|Original language||English (US)|
|Number of pages||19|
|Journal||Investigative Ophthalmology and Visual Science|
|State||Published - Jan 1 1981|
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience