Feline uveal melanoma model induced with feline sarcoma virus

Daniel Albert, J. A. Shadduck, J. L. Craft, J. Y. Niederkorn

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

This paper describes the first animal model of a virally induced uveal melanoma. Tumors developed following the injection of an RNA tumor virus, i.e., Gardner strain feline sarcoma virus, into the anterior chamber of newborn kitterns. Histogically, the tumors were found to be iris and ciliary body melanomas, many of which showed invasion. The histology and ultrastructure of those tumors are described.

Original languageEnglish (US)
Pages (from-to)606-624
Number of pages19
JournalInvestigative Ophthalmology and Visual Science
Volume20
Issue number5
StatePublished - Jan 1 1981
Externally publishedYes

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Feline Sarcoma Viruses
Felidae
Neoplasms
Ciliary Body
Anterior Chamber
Iris
Retroviridae
Melanoma
Histology
Animal Models
Injections
Uveal melanoma

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Albert, D., Shadduck, J. A., Craft, J. L., & Niederkorn, J. Y. (1981). Feline uveal melanoma model induced with feline sarcoma virus. Investigative Ophthalmology and Visual Science, 20(5), 606-624.

Feline uveal melanoma model induced with feline sarcoma virus. / Albert, Daniel; Shadduck, J. A.; Craft, J. L.; Niederkorn, J. Y.

In: Investigative Ophthalmology and Visual Science, Vol. 20, No. 5, 01.01.1981, p. 606-624.

Research output: Contribution to journalArticle

Albert, D, Shadduck, JA, Craft, JL & Niederkorn, JY 1981, 'Feline uveal melanoma model induced with feline sarcoma virus', Investigative Ophthalmology and Visual Science, vol. 20, no. 5, pp. 606-624.
Albert, Daniel ; Shadduck, J. A. ; Craft, J. L. ; Niederkorn, J. Y. / Feline uveal melanoma model induced with feline sarcoma virus. In: Investigative Ophthalmology and Visual Science. 1981 ; Vol. 20, No. 5. pp. 606-624.
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