Febrile Ulceronecrotic Mucha-Habermann Disease: Two Cases with Excellent Response to Methotrexate

Kelly Griffith-Bauer, Sabra L. Leitenberger, Alfons Krol

Research output: Contribution to journalShort surveypeer-review

9 Scopus citations

Abstract

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD), a severe form of pityriasis lichenoides et varioliformis acuta (PLEVA), featuring large, ulcerative, necrotic skin plaques, high fever, and other systemic symptoms, is a rare disorder of unknown etiology. No randomized controlled trials have established treatment guidelines and multiple modalities are often employed, making it difficult to assess the efficacy of any single agent. We report two cases of this condition in which treatment with methotrexate plus antibiotic treatment for superinfection led to rapid improvement.

Original languageEnglish (US)
Pages (from-to)e307-e308
JournalPediatric dermatology
Volume32
Issue number6
DOIs
StatePublished - Nov 1 2015

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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