TY - JOUR
T1 - Febrile Ulceronecrotic Mucha-Habermann Disease
T2 - Two Cases with Excellent Response to Methotrexate
AU - Griffith-Bauer, Kelly
AU - Leitenberger, Sabra L.
AU - Krol, Alfons
N1 - Publisher Copyright:
© 2015 Wiley Periodicals, Inc.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Febrile ulceronecrotic Mucha-Habermann disease (FUMHD), a severe form of pityriasis lichenoides et varioliformis acuta (PLEVA), featuring large, ulcerative, necrotic skin plaques, high fever, and other systemic symptoms, is a rare disorder of unknown etiology. No randomized controlled trials have established treatment guidelines and multiple modalities are often employed, making it difficult to assess the efficacy of any single agent. We report two cases of this condition in which treatment with methotrexate plus antibiotic treatment for superinfection led to rapid improvement.
AB - Febrile ulceronecrotic Mucha-Habermann disease (FUMHD), a severe form of pityriasis lichenoides et varioliformis acuta (PLEVA), featuring large, ulcerative, necrotic skin plaques, high fever, and other systemic symptoms, is a rare disorder of unknown etiology. No randomized controlled trials have established treatment guidelines and multiple modalities are often employed, making it difficult to assess the efficacy of any single agent. We report two cases of this condition in which treatment with methotrexate plus antibiotic treatment for superinfection led to rapid improvement.
UR - http://www.scopus.com/inward/record.url?scp=84948712995&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948712995&partnerID=8YFLogxK
U2 - 10.1111/pde.12687
DO - 10.1111/pde.12687
M3 - Short survey
C2 - 26584702
AN - SCOPUS:84948712995
SN - 0736-8046
VL - 32
SP - e307-e308
JO - Pediatric dermatology
JF - Pediatric dermatology
IS - 6
ER -