Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry

Hrebesh M. Subhash, Anh Nguyen-Huynh, Ruikang K. Wang, Steven L. Jacques, Niloy Choudhury, Alfred L. Nuttall

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

We describe a novel application of spectral-domain phase-sensitive optical coherence tomography (SD PS-OCT) to detect the tiny motions of the middle ear structures, such as the tympanic membrane and ossicular chain, and their morphological features for differential diagnosis of CHL. This technique has the potential to provide meaningful vibration of ossicles with a vibration sensitivity of ∼0.5 nm at 1 kHz of acoustic stimulation. To the best of our knowledge, this is the first demonstration of depth-resolved vibration imaging of ossicles with a PS-OCT system at a nanometer scale.

Original languageEnglish (US)
Article number060505
JournalJournal of biomedical optics
Volume17
Issue number6
DOIs
StatePublished - Jun 2012

Keywords

  • Interferometry
  • Middle ear
  • Optical coherence tomography
  • Phase-sensitive imaging
  • Vibrometry

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

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