Abstract
• Based on consensus, FTT is best considered a physical sign of undernutrition and not a clinical syndrome caused by "organic" or "nonorganic" factors. (1)(2) • Based on strong research evidence, infants and young children may cross major percentile lines on growth curves during a normal course of growth. Therefore, documentation of weights or lengths falling off of growth channels is not, by itself, proof of FTT. (3) • Based on conflicting research evidence, it is unclear how many children have adverse neurodevelopmental outcomes from FTT. (4)(5)(6)(7)(8) • Based on some research evidence, extensive laboratory screening is of little utility in the evaluation of FTT. (12) • Based on some research evidence, certain children who appear to have FTT may be biologically programmed to be smaller and thinner than most children. Insulin resistance may be a mechanism, and aggressive nutritional intervention may put these children at risk of developing metabolic syndrome. (13)(14)(15).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 100-108 |
| Number of pages | 9 |
| Journal | Pediatrics in Review |
| Volume | 32 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2011 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Failure to thrive : Current clinical concepts. / Jaffe, Arthur.
In: Pediatrics in Review, Vol. 32, No. 3, 03.2011, p. 100-108.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Failure to thrive
T2 - Current clinical concepts
AU - Jaffe, Arthur
PY - 2011/3
Y1 - 2011/3
N2 - • Based on consensus, FTT is best considered a physical sign of undernutrition and not a clinical syndrome caused by "organic" or "nonorganic" factors. (1)(2) • Based on strong research evidence, infants and young children may cross major percentile lines on growth curves during a normal course of growth. Therefore, documentation of weights or lengths falling off of growth channels is not, by itself, proof of FTT. (3) • Based on conflicting research evidence, it is unclear how many children have adverse neurodevelopmental outcomes from FTT. (4)(5)(6)(7)(8) • Based on some research evidence, extensive laboratory screening is of little utility in the evaluation of FTT. (12) • Based on some research evidence, certain children who appear to have FTT may be biologically programmed to be smaller and thinner than most children. Insulin resistance may be a mechanism, and aggressive nutritional intervention may put these children at risk of developing metabolic syndrome. (13)(14)(15).
AB - • Based on consensus, FTT is best considered a physical sign of undernutrition and not a clinical syndrome caused by "organic" or "nonorganic" factors. (1)(2) • Based on strong research evidence, infants and young children may cross major percentile lines on growth curves during a normal course of growth. Therefore, documentation of weights or lengths falling off of growth channels is not, by itself, proof of FTT. (3) • Based on conflicting research evidence, it is unclear how many children have adverse neurodevelopmental outcomes from FTT. (4)(5)(6)(7)(8) • Based on some research evidence, extensive laboratory screening is of little utility in the evaluation of FTT. (12) • Based on some research evidence, certain children who appear to have FTT may be biologically programmed to be smaller and thinner than most children. Insulin resistance may be a mechanism, and aggressive nutritional intervention may put these children at risk of developing metabolic syndrome. (13)(14)(15).
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U2 - 10.1542/pir.32-3-100
DO - 10.1542/pir.32-3-100
M3 - Article
VL - 32
SP - 100
EP - 108
JO - Pediatrics in Review
JF - Pediatrics in Review
SN - 0191-9601
IS - 3
ER -