Factors and outcomes associated with longer latency in preterm premature rupture of membranes

Natali Aziz, Yvonne W. Cheng, Aaron Caughey

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective. To examine factors and outcomes associated with latency in preterm premature rupture of membranes (PPROM). Methods. A retrospective cohort study was conducted of all deliveries with a diagnosis of PPROM at 24-34 weeks of gestation at an academic medical center for the period 1980-2001. Gestational age at PPROM was examined as the primary independent variable. Primary outcome was duration from rupture of membranes until delivery. The association with neonatal and maternal perinatal morbidity was examined with duration of latency. Dichotomous outcomes were compared using the Chi-square test. Multivariable regression analyses were performed to control for potential confounding variables. Results. One thousand one hundred and sixty-eight patients were identified. Latency duration was inversely associated with gestational age at time of PPROM (p

Original languageEnglish (US)
Pages (from-to)821-825
Number of pages5
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume21
Issue number11
DOIs
StatePublished - 2008
Externally publishedYes

Fingerprint

Gestational Age
Confounding Factors (Epidemiology)
Chi-Square Distribution
Rupture
Cohort Studies
Retrospective Studies
Regression Analysis
Mothers
Morbidity
Pregnancy
Membranes
Preterm Premature Rupture of the Membranes

Keywords

  • Gestational age
  • Latency duration
  • Perinatal outcomes
  • PPROM

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Factors and outcomes associated with longer latency in preterm premature rupture of membranes. / Aziz, Natali; Cheng, Yvonne W.; Caughey, Aaron.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 21, No. 11, 2008, p. 821-825.

Research output: Contribution to journalArticle

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