Factors Affecting Mortality of Gram-Negative Rod Bacteremia

Richard Bryant, Antoinette F. Hood, Charles E. Hood, M. Glenn Koenig

Research output: Contribution to journalArticle

219 Citations (Scopus)

Abstract

A retrospective analysis of 218 patients with gram-negative rod bacteremia was made in order to evaluate factors affecting survival of these patients. In patients with comparable underlying disease, no significant increase in mortality was found to be associated with race, sex, hospital service, level of leukocyte count, hospital-acquired infection, or the portal of entry of infection. Factors associated with an increased mortality from gram-negative rod bacteremia were shock, azotemia, Pseudomonas bacteremia, and low or normal temperature during bacteremia. Appropriate antibiotic therapy significantly increased survival of all patients except those with the most severe underlying disease. A combination of antibiotics including colistimethate sodium, kanamycin sulfate, and penicillin, or its congeners, provided effective antimicrobial therapy against a higher percent of bacterial strains causing bacteremia than other drug regimens used during the period of this study.

Original languageEnglish (US)
Pages (from-to)120-128
Number of pages9
JournalArchives of Internal Medicine
Volume127
Issue number1
DOIs
StatePublished - 1971
Externally publishedYes

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Bacteremia
Mortality
Anti-Bacterial Agents
Azotemia
Kanamycin
Penicillin G
Survival
Cross Infection
Pseudomonas
Leukocyte Count
Shock
Temperature
Therapeutics
Infection
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Factors Affecting Mortality of Gram-Negative Rod Bacteremia. / Bryant, Richard; Hood, Antoinette F.; Hood, Charles E.; Koenig, M. Glenn.

In: Archives of Internal Medicine, Vol. 127, No. 1, 1971, p. 120-128.

Research output: Contribution to journalArticle

Bryant, Richard ; Hood, Antoinette F. ; Hood, Charles E. ; Koenig, M. Glenn. / Factors Affecting Mortality of Gram-Negative Rod Bacteremia. In: Archives of Internal Medicine. 1971 ; Vol. 127, No. 1. pp. 120-128.
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