Extracorporeal lung support in trauma patients with severe chest injury and acute lung failure

A 10-year institutional experience

Michael Ried, Thomas Bein, Alois Philipp, Thomas Müller, Bernhard Graf, Christof Schmid, David Zonies, Claudius Diez, Hans Stefan Hofmann

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Introduction: Severe trauma with concomitant chest injury is frequently associated with acute lung failure (ALF). This report summarizes our experience with extracorporeal lung support (ELS) in thoracic trauma patients treated at the University Medical Center Regensburg.Methods: A retrospective, observational analysis of prospectively collected data (Regensburg ECMO Registry database) was performed for all consecutive trauma patients with acute pulmonary failure requiring ELS during a 10-year interval.Results: Between April 2002 and April 2012, 52 patients (49 male, three female) with severe thoracic trauma and ALF refractory to conventional therapy required ELS. The mean age was 32 ± 14 years (range, 16 to 72 years). Major traffic accident (73%) was the most common trauma, followed by blast injury (17%), deep fall (8%) and blunt trauma (2%). The mean Injury Severity Score was 58.9 ± 10.5, the mean lung injury score was 3.3 ± 0.6 and the Sequential Organ Failure Assessment score was 10.5 ± 3. Twenty-six patients required pumpless extracorporeal lung assist (PECLA) and 26 patients required veno-venous extracorporeal membrane oxygenation (vv-ECMO) for primary post-traumatic respiratory failure. The mean time to ELS support was 5.2 ± 7.7 days (range,

Original languageEnglish (US)
Article numberR110
JournalCritical Care
Volume17
Issue number3
DOIs
StatePublished - Jun 20 2013
Externally publishedYes

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Thoracic Injuries
antineoplaston A10
Lung
Wounds and Injuries
Thorax
Blast Injuries
Organ Dysfunction Scores
Extracorporeal Membrane Oxygenation
Injury Severity Score
Traffic Accidents
Lung Injury
Respiratory Insufficiency
Registries
Databases

Keywords

  • Acute lung failure
  • Chest injury
  • Extracorporeal lung support
  • Extracorporeal membrane oxygenation
  • Trauma

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Medicine(all)

Cite this

Extracorporeal lung support in trauma patients with severe chest injury and acute lung failure : A 10-year institutional experience. / Ried, Michael; Bein, Thomas; Philipp, Alois; Müller, Thomas; Graf, Bernhard; Schmid, Christof; Zonies, David; Diez, Claudius; Hofmann, Hans Stefan.

In: Critical Care, Vol. 17, No. 3, R110, 20.06.2013.

Research output: Contribution to journalArticle

Ried, Michael ; Bein, Thomas ; Philipp, Alois ; Müller, Thomas ; Graf, Bernhard ; Schmid, Christof ; Zonies, David ; Diez, Claudius ; Hofmann, Hans Stefan. / Extracorporeal lung support in trauma patients with severe chest injury and acute lung failure : A 10-year institutional experience. In: Critical Care. 2013 ; Vol. 17, No. 3.
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