Extracellular signal-regulated protein kinase activation is required for the anti-hypertrophic effect of atrial natriuretic factor in neonatal rat ventricular myocytes

Medicine & Life Sciences

• Atrial Natriuretic Factor 51%
• Extracellular Signal-Regulated MAP Kinases 50%
• Protein Kinases 43%
• Muscle Cells 42%
• Phenylephrine 21%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 11%
• Mitogen-Activated Protein Kinase Kinases 10%
• Phosphorylation 9%
• Mitogen-Activated Protein Kinases 6%
• Atrial Natriuretic Factor Receptors 5%
• Adrenergic Agonists 4%
• Guanylate Cyclase 4%
• Cardiac Myocytes 3%
• Hypertrophy 3%
• Protein Isoforms 2%
• Signal Transduction 2%
• Phosphotransferases 2%
• Heart 2%
• In Vitro Techniques 1%

Chemical Compounds

• Antihypertrophic 100%
• Diuretic Agent 24%
• Protein 19%
• Phenylephrine 18%
• Adrenergic Agonist 7%
• EC 2.7.12.2 (Mitogen-Activated Protein Kinase Kinase) Inhibitor 6%
• Signal Transduction 4%
• Additive 2%