Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas

Matthew J. McGirt, Kaisorn L. Chaichana, Frank J. Attenello, Jon D. Weingart, Khoi Than, Peter C. Burger, Alessandro Olivi, Henry Brem, Alfredo Quinoñes-Hinojosa

Research output: Contribution to journalArticle

291 Citations (Scopus)

Abstract

OBJECTIVE: It remains unknown whether the extent of surgical resection affects survival or disease progression in patients with supratentorial low-grade gliomas. METHODS: We conducted a retrospective cohort study (n = 170) between 1996 and 2007 at a single institution to determine whether increasing extent of surgical resection was associated with improved progression-free survival (PFS) and overall survival (OS). Surgical resection of gliomas defined as gross total resection (GTR) (complete resection of the preoperative fluid-attenuated inversion recovery signal abnormality), near total resection (NTR) (

Original languageEnglish (US)
Pages (from-to)700-707
Number of pages8
JournalNeurosurgery
Volume63
Issue number4
DOIs
StatePublished - Oct 2008
Externally publishedYes

Fingerprint

Glioma
Survival
Disease-Free Survival
Disease Progression
Cohort Studies
Retrospective Studies

Keywords

  • Astrocytoma
  • Extent of resection
  • Low-grade
  • Survival

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

McGirt, M. J., Chaichana, K. L., Attenello, F. J., Weingart, J. D., Than, K., Burger, P. C., ... Quinoñes-Hinojosa, A. (2008). Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. Neurosurgery, 63(4), 700-707. https://doi.org/10.1227/01.NEU.0000325729.41085.73

Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. / McGirt, Matthew J.; Chaichana, Kaisorn L.; Attenello, Frank J.; Weingart, Jon D.; Than, Khoi; Burger, Peter C.; Olivi, Alessandro; Brem, Henry; Quinoñes-Hinojosa, Alfredo.

In: Neurosurgery, Vol. 63, No. 4, 10.2008, p. 700-707.

Research output: Contribution to journalArticle

McGirt, MJ, Chaichana, KL, Attenello, FJ, Weingart, JD, Than, K, Burger, PC, Olivi, A, Brem, H & Quinoñes-Hinojosa, A 2008, 'Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas', Neurosurgery, vol. 63, no. 4, pp. 700-707. https://doi.org/10.1227/01.NEU.0000325729.41085.73
McGirt, Matthew J. ; Chaichana, Kaisorn L. ; Attenello, Frank J. ; Weingart, Jon D. ; Than, Khoi ; Burger, Peter C. ; Olivi, Alessandro ; Brem, Henry ; Quinoñes-Hinojosa, Alfredo. / Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. In: Neurosurgery. 2008 ; Vol. 63, No. 4. pp. 700-707.
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