Extended axial imaging range, widefield swept source optical coherence tomography angiography

Gangjun Liu, Jianlong Yang, Jie Wang, Yan Li, Pengxiao Zang, Yali Jia, David Huang

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

We developed a high-speed, swept source OCT system for widefield OCT angiography (OCTA) imaging. The system has an extended axial imaging range of 6.6 mm. An electrical lens is used for fast, automatic focusing. The recently developed split-spectrum amplitude and phase-gradient angiography allow high-resolution OCTA imaging with only two B-scan repetitions. An improved post-processing algorithm effectively removed trigger jitter artifacts and reduced noise in the flow signal. We demonstrated high contrast 3 mm×3 mm OCTA image with 400×400 pixels acquired in 3 seconds and high-definition 8 mm×6 mm and 12 mm×6 mm OCTA images with 850×400 pixels obtained in 4 seconds. A widefield 8 mm×11 mm OCTA image is produced by montaging two 8 mm×6 mm scans. An ultra-widefield (with a maximum of 22 mm along both vertical and horizontal directions) capillary-resolution OCTA image is obtained by montaging six 12 mm×6 mm scans.

Original languageEnglish (US)
Pages (from-to)1464-1472
Number of pages9
JournalJournal of Biophotonics
Volume10
Issue number11
DOIs
StatePublished - Nov 2017

Keywords

  • Optical coherence tomography
  • optical coherence tomography angiography
  • widefield imaging.

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Physics and Astronomy(all)

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