Expression of the c-myc Protooncogene in Human Prostatic Carcinoma and Benign Prostatic Hyperplasia

William Fleming, Andre Hamel, Janice G. Dodd, Robert J. Matusik, Robert MacDonald, Ernest Ramsey, Norman M. Pettiarew, Brian Johnston

Research output: Contribution to journalArticle

152 Citations (Scopus)

Abstract

We have examined the level of c-myc transcripts in prostate tissue obtained from patients with both benign prostatic hyperplasia and adenocarcinoma of the prostate. A significantly higher level of c-myc transcripts is observed in patients with adenocarcinoma (P < 0.05). In addition, a subset of patients with adenocarcinoma had levels of c-myc transcripts 2-fold higher than the mean level for this group. These preliminary results indicate that the investigation of c-myc levels as a prognostic indicator in prostatic carcinoma is warranted.

Original languageEnglish (US)
Pages (from-to)1535-1538
Number of pages4
JournalCancer Research
Volume46
Issue number3
StatePublished - Mar 1 1986
Externally publishedYes

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Prostatic Hyperplasia
Adenocarcinoma
Carcinoma
Prostate

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Fleming, W., Hamel, A., Dodd, J. G., Matusik, R. J., MacDonald, R., Ramsey, E., ... Johnston, B. (1986). Expression of the c-myc Protooncogene in Human Prostatic Carcinoma and Benign Prostatic Hyperplasia. Cancer Research, 46(3), 1535-1538.

Expression of the c-myc Protooncogene in Human Prostatic Carcinoma and Benign Prostatic Hyperplasia. / Fleming, William; Hamel, Andre; Dodd, Janice G.; Matusik, Robert J.; MacDonald, Robert; Ramsey, Ernest; Pettiarew, Norman M.; Johnston, Brian.

In: Cancer Research, Vol. 46, No. 3, 01.03.1986, p. 1535-1538.

Research output: Contribution to journalArticle

Fleming, W, Hamel, A, Dodd, JG, Matusik, RJ, MacDonald, R, Ramsey, E, Pettiarew, NM & Johnston, B 1986, 'Expression of the c-myc Protooncogene in Human Prostatic Carcinoma and Benign Prostatic Hyperplasia', Cancer Research, vol. 46, no. 3, pp. 1535-1538.
Fleming W, Hamel A, Dodd JG, Matusik RJ, MacDonald R, Ramsey E et al. Expression of the c-myc Protooncogene in Human Prostatic Carcinoma and Benign Prostatic Hyperplasia. Cancer Research. 1986 Mar 1;46(3):1535-1538.
Fleming, William ; Hamel, Andre ; Dodd, Janice G. ; Matusik, Robert J. ; MacDonald, Robert ; Ramsey, Ernest ; Pettiarew, Norman M. ; Johnston, Brian. / Expression of the c-myc Protooncogene in Human Prostatic Carcinoma and Benign Prostatic Hyperplasia. In: Cancer Research. 1986 ; Vol. 46, No. 3. pp. 1535-1538.
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