Expert Opinion: Omega-3 Fatty Acids and Bleeding-Cause for Concern?

William Harris

Research output: Contribution to journalArticle

150 Scopus citations


Omega-3 fatty acid ethyl esters have well-known triglyceride-lowering properties and were shown >30 years ago to inhibit platelet function. With the recent US Food and Drug Administration (FDA) approval of these agents for treating severe triglyceride elevations, concerns about excess bleeding naturally arise. However, an objective assessment of the evidence for clinically significant bleeding reveals that such concerns are unfounded. As such, the benefits of triglyceride lowering with omega-3 fatty acids more than outweigh any theoretical risks for increased bleeding.

Original languageEnglish (US)
JournalAmerican Journal of Cardiology
Issue number6 SUPPL. 1
Publication statusPublished - Mar 19 2007
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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