Experience-dependent development of spinal motor neurons

Fiona M. Inglis, Katharine Zuckerman, Robert G. Kalb

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Locomotor activity in many species undergoes pronounced alterations in early postnatal life, and environmental cues may be responsible for modifying this process. To determine how these events are reflected in the nervous system, we studied rats reared under two different conditions - the presence or absence of gravity - in which the performance of motor operations differed. We found a significant effect of rearing environment on the size and complexity of dendritic architecture of spinal motor neurons, particularly those that are likely to participate in postural control. These results provide evidence that neurons subserving motor function undergo activity-dependent maturation in early postnatal life in a manner analogous to sensory systems.

Original languageEnglish (US)
Pages (from-to)299-305
Number of pages7
JournalNeuron
Volume26
Issue number2
StatePublished - 2000
Externally publishedYes

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Motor Neurons
Gravitation
Locomotion
Nervous System
Cues

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Inglis, F. M., Zuckerman, K., & Kalb, R. G. (2000). Experience-dependent development of spinal motor neurons. Neuron, 26(2), 299-305.

Experience-dependent development of spinal motor neurons. / Inglis, Fiona M.; Zuckerman, Katharine; Kalb, Robert G.

In: Neuron, Vol. 26, No. 2, 2000, p. 299-305.

Research output: Contribution to journalArticle

Inglis, FM, Zuckerman, K & Kalb, RG 2000, 'Experience-dependent development of spinal motor neurons', Neuron, vol. 26, no. 2, pp. 299-305.
Inglis, Fiona M. ; Zuckerman, Katharine ; Kalb, Robert G. / Experience-dependent development of spinal motor neurons. In: Neuron. 2000 ; Vol. 26, No. 2. pp. 299-305.
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