TY - JOUR
T1 - Exercise for individuals with bone metastases
T2 - A systematic review
AU - Weller, Sarah
AU - Hart, Nicolas H.
AU - Bolam, Kate A.
AU - Mansfield, Sami
AU - Santa Mina, Daniel
AU - Winters-Stone, Kerri M.
AU - Campbell, Anna
AU - Rosenberger, Friederike
AU - Wiskemann, Joachim
AU - Quist, Morten
AU - Cormie, Prue
AU - Goulart, Jennifer
AU - Campbell, Kristin L.
N1 - Publisher Copyright:
© 2021 The Authors
PY - 2021/10
Y1 - 2021/10
N2 - Background: Exercise has the potential to improve physical function and quality of life in individuals with bone metastases but is often avoided due to safety concerns. This systematic review summarizes the safety, feasibility and efficacy of exercise in controlled trials that include individuals with bone metastases. Methods: MEDLINE, Embase, Pubmed, CINAHL, PEDro and CENTRAL databases were searched to July 16, 2020. Results: A total of 17 trials were included incorporating aerobic exercise, resistance exercise or soccer interventions. Few (n = 4, 0.5%) serious adverse events were attributed to exercise participation, with none related to bone metastases. Mixed efficacy results were found, with exercise eliciting positive changes or no change. The majority of trials included an element of supervised exercise instruction (n = 16, 94%) and were delivered by qualified exercise professionals (n = 13, 76%). Conclusions: Exercise appears safe and feasible for individuals with bone metastases when it includes an element of supervised exercise instruction.
AB - Background: Exercise has the potential to improve physical function and quality of life in individuals with bone metastases but is often avoided due to safety concerns. This systematic review summarizes the safety, feasibility and efficacy of exercise in controlled trials that include individuals with bone metastases. Methods: MEDLINE, Embase, Pubmed, CINAHL, PEDro and CENTRAL databases were searched to July 16, 2020. Results: A total of 17 trials were included incorporating aerobic exercise, resistance exercise or soccer interventions. Few (n = 4, 0.5%) serious adverse events were attributed to exercise participation, with none related to bone metastases. Mixed efficacy results were found, with exercise eliciting positive changes or no change. The majority of trials included an element of supervised exercise instruction (n = 16, 94%) and were delivered by qualified exercise professionals (n = 13, 76%). Conclusions: Exercise appears safe and feasible for individuals with bone metastases when it includes an element of supervised exercise instruction.
KW - bone neoplasms
KW - exercise
KW - neoplasm metastasis
KW - neoplasms
KW - rehabilitation
KW - sports
KW - systematic review
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U2 - 10.1016/j.critrevonc.2021.103433
DO - 10.1016/j.critrevonc.2021.103433
M3 - Review article
C2 - 34358650
AN - SCOPUS:85116037440
SN - 1040-8428
VL - 166
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
M1 - 103433
ER -