Excision of pyrimidine dimers in toluene treated Escherichia coli

W. A. Deutsch, J. W. Dorson, R. E. Moses

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Toluene treated cells were used for examining excision of pyrimidine dimers in E. coli strains W3110, DM845 (uvrA-), P3478 (polA-), and KS5064 (polA(ex1)). Excision occurring in toluene treated cells is rapid, adenosine 5' triphosphate dependent, and requires the uvrA gene function. In strains lacking either the polymerizing or 5'→ 3' exonucleolytic activity of dioxyribonucleic acid polymerase I, excision does occur. However, both in vivo and in vitro, the excision in such strains is initially slower than wild type.

Original languageEnglish (US)
Pages (from-to)220-224
Number of pages5
JournalJournal of bacteriology
Issue number1
StatePublished - Dec 1 1976

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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