@inbook{6145a3acca914c42947528c10a0eda72,
title = "Ex vivo studies of optic nerve axon electrophysiology",
abstract = "The use of ex vivo compound action potential (CAP) recordings from intact optic nerves is an ideal model to study white matter function without the influence of gray matter. Here, we describe how freshly dissected optic nerves are placed in a humidified recording chamber and how evoked CAPs are recorded and monitored in real time for up to 10 h. Evoked CAP recordings allow for white matter to be studied under acute challenges such as anoxia, hypoxia, aglycemia, and ischemia.",
keywords = "Aglycemia, Anoxia, Axon, Compound action potential, Ischemia, Optic nerve, White matter",
author = "Chinthasagar Bastian and Sylvain Brunet and Selva Baltan",
note = "Funding Information: This work was supported by grants from National Institute on Aging (NIA) to Selva Baltan and NINDS to Sylvain Brunet and Selva Baltan, as well as a gift from Rose Mary Kubik. Selva Baltan has previously published as Selva Tekk{\"o}k. The authors thank Dr. Chris Nelson, medical writer, for his help in editing this chapter. Materials and data were provided by the Cleveland Clinic Foundation (CCF). All rights, title, and interest in the materials and data are owned by the CCF. Publisher Copyright: {\textcopyright} Springer Science+Business Media, LLC, part of Springer Nature 2020.",
year = "2020",
doi = "10.1007/978-1-0716-0585-1_13",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "169--177",
booktitle = "Methods in Molecular Biology",
}