Evolutionary history of chromosome 10 in primates

Lucia Carbone, Mario Ventura, Sergio Tempesta, Mariano Rocchi, Nicoletta Archidiacono

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

We have tracked the evolutionary history of chromosomes homologous to HSA 10 (PHYL-10) in primates using appropriate panels of PCP, YAC, and BAC probes. This approach allowed us to delineate more precisely the PHYL-10 constitution in the ancestor of catarrhine, platyrrhine, and prosimians. The results suggest that (i) in the ancestor of prosimians PHYL-10 was organized in two separate PHYL-10p and PHYL-10q chromosomes; (ii) in the progenitor of New World monkeys PHYL-10p was a separate chromosome, while PHYL-10q was associated with a chromosome homologous to HSA 16; (iii) in the ancestor of Old World monkeys PHYL-10 was a unique chromosome with a marker order corresponding to the orang form. We have also analyzed the cat, chosen as an outgroup for its very conserved karyotype. In agreement with published data our experiments show that the PHYL-10 in cat is structured in two blocks, PHYL-10p and PHYL-10q, both as part of larger chromosomes. The overall data indicate that, contrary to common opinion, PHYL-10p and PHYL-10q were distinct chromosomes in the primate ancestor. Analysis of the Saimiri sciureus (SSC) PHYL-10q marker order showed that it was isosequential with the Callithrix jacchus PHYL-10q, as well as with the PHYL-10q platyrrhine ancestral form. The SSC centromere, nevertheless, was located in a different chromosomal region, therefore suggesting that a centromeric repositioning event occurred in this species.

Original languageEnglish (US)
Pages (from-to)267-272
Number of pages6
JournalChromosoma
Volume111
Issue number4
StatePublished - Nov 2002
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 10
Primates
Chromosomes
Strepsirhini
Saimiri
Cats
Platyrrhini
Cercopithecidae
Callithrix
Centromere
Constitution and Bylaws
Karyotype
History

ASJC Scopus subject areas

  • Genetics

Cite this

Carbone, L., Ventura, M., Tempesta, S., Rocchi, M., & Archidiacono, N. (2002). Evolutionary history of chromosome 10 in primates. Chromosoma, 111(4), 267-272.

Evolutionary history of chromosome 10 in primates. / Carbone, Lucia; Ventura, Mario; Tempesta, Sergio; Rocchi, Mariano; Archidiacono, Nicoletta.

In: Chromosoma, Vol. 111, No. 4, 11.2002, p. 267-272.

Research output: Contribution to journalArticle

Carbone, L, Ventura, M, Tempesta, S, Rocchi, M & Archidiacono, N 2002, 'Evolutionary history of chromosome 10 in primates', Chromosoma, vol. 111, no. 4, pp. 267-272.
Carbone L, Ventura M, Tempesta S, Rocchi M, Archidiacono N. Evolutionary history of chromosome 10 in primates. Chromosoma. 2002 Nov;111(4):267-272.
Carbone, Lucia ; Ventura, Mario ; Tempesta, Sergio ; Rocchi, Mariano ; Archidiacono, Nicoletta. / Evolutionary history of chromosome 10 in primates. In: Chromosoma. 2002 ; Vol. 111, No. 4. pp. 267-272.
@article{4f5ae35183f241a2a45070da59221731,
title = "Evolutionary history of chromosome 10 in primates",
abstract = "We have tracked the evolutionary history of chromosomes homologous to HSA 10 (PHYL-10) in primates using appropriate panels of PCP, YAC, and BAC probes. This approach allowed us to delineate more precisely the PHYL-10 constitution in the ancestor of catarrhine, platyrrhine, and prosimians. The results suggest that (i) in the ancestor of prosimians PHYL-10 was organized in two separate PHYL-10p and PHYL-10q chromosomes; (ii) in the progenitor of New World monkeys PHYL-10p was a separate chromosome, while PHYL-10q was associated with a chromosome homologous to HSA 16; (iii) in the ancestor of Old World monkeys PHYL-10 was a unique chromosome with a marker order corresponding to the orang form. We have also analyzed the cat, chosen as an outgroup for its very conserved karyotype. In agreement with published data our experiments show that the PHYL-10 in cat is structured in two blocks, PHYL-10p and PHYL-10q, both as part of larger chromosomes. The overall data indicate that, contrary to common opinion, PHYL-10p and PHYL-10q were distinct chromosomes in the primate ancestor. Analysis of the Saimiri sciureus (SSC) PHYL-10q marker order showed that it was isosequential with the Callithrix jacchus PHYL-10q, as well as with the PHYL-10q platyrrhine ancestral form. The SSC centromere, nevertheless, was located in a different chromosomal region, therefore suggesting that a centromeric repositioning event occurred in this species.",
author = "Lucia Carbone and Mario Ventura and Sergio Tempesta and Mariano Rocchi and Nicoletta Archidiacono",
year = "2002",
month = "11",
language = "English (US)",
volume = "111",
pages = "267--272",
journal = "Chromosoma",
issn = "0009-5915",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "4",

}

TY - JOUR

T1 - Evolutionary history of chromosome 10 in primates

AU - Carbone, Lucia

AU - Ventura, Mario

AU - Tempesta, Sergio

AU - Rocchi, Mariano

AU - Archidiacono, Nicoletta

PY - 2002/11

Y1 - 2002/11

N2 - We have tracked the evolutionary history of chromosomes homologous to HSA 10 (PHYL-10) in primates using appropriate panels of PCP, YAC, and BAC probes. This approach allowed us to delineate more precisely the PHYL-10 constitution in the ancestor of catarrhine, platyrrhine, and prosimians. The results suggest that (i) in the ancestor of prosimians PHYL-10 was organized in two separate PHYL-10p and PHYL-10q chromosomes; (ii) in the progenitor of New World monkeys PHYL-10p was a separate chromosome, while PHYL-10q was associated with a chromosome homologous to HSA 16; (iii) in the ancestor of Old World monkeys PHYL-10 was a unique chromosome with a marker order corresponding to the orang form. We have also analyzed the cat, chosen as an outgroup for its very conserved karyotype. In agreement with published data our experiments show that the PHYL-10 in cat is structured in two blocks, PHYL-10p and PHYL-10q, both as part of larger chromosomes. The overall data indicate that, contrary to common opinion, PHYL-10p and PHYL-10q were distinct chromosomes in the primate ancestor. Analysis of the Saimiri sciureus (SSC) PHYL-10q marker order showed that it was isosequential with the Callithrix jacchus PHYL-10q, as well as with the PHYL-10q platyrrhine ancestral form. The SSC centromere, nevertheless, was located in a different chromosomal region, therefore suggesting that a centromeric repositioning event occurred in this species.

AB - We have tracked the evolutionary history of chromosomes homologous to HSA 10 (PHYL-10) in primates using appropriate panels of PCP, YAC, and BAC probes. This approach allowed us to delineate more precisely the PHYL-10 constitution in the ancestor of catarrhine, platyrrhine, and prosimians. The results suggest that (i) in the ancestor of prosimians PHYL-10 was organized in two separate PHYL-10p and PHYL-10q chromosomes; (ii) in the progenitor of New World monkeys PHYL-10p was a separate chromosome, while PHYL-10q was associated with a chromosome homologous to HSA 16; (iii) in the ancestor of Old World monkeys PHYL-10 was a unique chromosome with a marker order corresponding to the orang form. We have also analyzed the cat, chosen as an outgroup for its very conserved karyotype. In agreement with published data our experiments show that the PHYL-10 in cat is structured in two blocks, PHYL-10p and PHYL-10q, both as part of larger chromosomes. The overall data indicate that, contrary to common opinion, PHYL-10p and PHYL-10q were distinct chromosomes in the primate ancestor. Analysis of the Saimiri sciureus (SSC) PHYL-10q marker order showed that it was isosequential with the Callithrix jacchus PHYL-10q, as well as with the PHYL-10q platyrrhine ancestral form. The SSC centromere, nevertheless, was located in a different chromosomal region, therefore suggesting that a centromeric repositioning event occurred in this species.

UR - http://www.scopus.com/inward/record.url?scp=0036870729&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036870729&partnerID=8YFLogxK

M3 - Article

C2 - 12424526

AN - SCOPUS:0036870729

VL - 111

SP - 267

EP - 272

JO - Chromosoma

JF - Chromosoma

SN - 0009-5915

IS - 4

ER -