Abstract
• Purpose: To measure accuracy and speed for detection of vascular progression in retinopathy of prematurity (ROP) from serial images. Two strategies are compared: static side-by-side presentation and dynamic flickering of superimposed image pairs. • Design: Prospective comparative study. • Methods: Fifteen de-identified, wide-angle retinal image pairs were taken from infants who eventually developed plus disease. Image pairs representing vascular disease progression were taken ≥1 week apart, and control images without progression were taken on the same day. Dynamic flickering pairs were created by digital image registration. Ten experts independently reviewed each image pair on a secure website using both strategies, and were asked to identify progression or state that images were identical. Accuracy and speed were measured, using examination date and ophthalmoscopic findings as a reference standard. • Results: Using static images, experts were accurate in a mean (%) ± standard deviation (SD) of 11.4 of 15 (76%) ± 1.7 image pairs. Using dynamic flickering images, experts were accurate in a mean (%) ± SD of 11.3 of 15 (75%) ± 1.7 image pairs. There was no significant difference in accuracy between these strategies (P =.420). Diagnostic speed was faster using dynamic flickering (24.7 ± 8.3 seconds) vs static side-by-side images (40.3 ± 18.3 seconds) (P =.002). Experts reported higher confidence when interpreting dynamic flickering images (P =.001). • Conclusions: Retinal imaging provides objective documentation of vascular appearance, with potentially improved ability to recognize ROP progression compared to standard ophthalmoscopy. Speed of identifying vascular progression was faster by review of dynamic flickering image pairs than by static side-by-side images, although there was no difference in accuracy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 544-551 |
| Number of pages | 8 |
| Journal | American Journal of Ophthalmology |
| Volume | 153 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2012 |
Fingerprint
ASJC Scopus subject areas
- Ophthalmology
Cite this
Evaluation of vascular disease progression in retinopathy of prematurity using static and dynamic retinal images. / Myung, Jane S.; Gelman, Rony; Aaker, Grant D.; Radcliffe, Nathan M.; Chan, R. V Paul; Chiang, Michael.
In: American Journal of Ophthalmology, Vol. 153, No. 3, 03.2012, p. 544-551.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evaluation of vascular disease progression in retinopathy of prematurity using static and dynamic retinal images
AU - Myung, Jane S.
AU - Gelman, Rony
AU - Aaker, Grant D.
AU - Radcliffe, Nathan M.
AU - Chan, R. V Paul
AU - Chiang, Michael
PY - 2012/3
Y1 - 2012/3
N2 - • Purpose: To measure accuracy and speed for detection of vascular progression in retinopathy of prematurity (ROP) from serial images. Two strategies are compared: static side-by-side presentation and dynamic flickering of superimposed image pairs. • Design: Prospective comparative study. • Methods: Fifteen de-identified, wide-angle retinal image pairs were taken from infants who eventually developed plus disease. Image pairs representing vascular disease progression were taken ≥1 week apart, and control images without progression were taken on the same day. Dynamic flickering pairs were created by digital image registration. Ten experts independently reviewed each image pair on a secure website using both strategies, and were asked to identify progression or state that images were identical. Accuracy and speed were measured, using examination date and ophthalmoscopic findings as a reference standard. • Results: Using static images, experts were accurate in a mean (%) ± standard deviation (SD) of 11.4 of 15 (76%) ± 1.7 image pairs. Using dynamic flickering images, experts were accurate in a mean (%) ± SD of 11.3 of 15 (75%) ± 1.7 image pairs. There was no significant difference in accuracy between these strategies (P =.420). Diagnostic speed was faster using dynamic flickering (24.7 ± 8.3 seconds) vs static side-by-side images (40.3 ± 18.3 seconds) (P =.002). Experts reported higher confidence when interpreting dynamic flickering images (P =.001). • Conclusions: Retinal imaging provides objective documentation of vascular appearance, with potentially improved ability to recognize ROP progression compared to standard ophthalmoscopy. Speed of identifying vascular progression was faster by review of dynamic flickering image pairs than by static side-by-side images, although there was no difference in accuracy.
AB - • Purpose: To measure accuracy and speed for detection of vascular progression in retinopathy of prematurity (ROP) from serial images. Two strategies are compared: static side-by-side presentation and dynamic flickering of superimposed image pairs. • Design: Prospective comparative study. • Methods: Fifteen de-identified, wide-angle retinal image pairs were taken from infants who eventually developed plus disease. Image pairs representing vascular disease progression were taken ≥1 week apart, and control images without progression were taken on the same day. Dynamic flickering pairs were created by digital image registration. Ten experts independently reviewed each image pair on a secure website using both strategies, and were asked to identify progression or state that images were identical. Accuracy and speed were measured, using examination date and ophthalmoscopic findings as a reference standard. • Results: Using static images, experts were accurate in a mean (%) ± standard deviation (SD) of 11.4 of 15 (76%) ± 1.7 image pairs. Using dynamic flickering images, experts were accurate in a mean (%) ± SD of 11.3 of 15 (75%) ± 1.7 image pairs. There was no significant difference in accuracy between these strategies (P =.420). Diagnostic speed was faster using dynamic flickering (24.7 ± 8.3 seconds) vs static side-by-side images (40.3 ± 18.3 seconds) (P =.002). Experts reported higher confidence when interpreting dynamic flickering images (P =.001). • Conclusions: Retinal imaging provides objective documentation of vascular appearance, with potentially improved ability to recognize ROP progression compared to standard ophthalmoscopy. Speed of identifying vascular progression was faster by review of dynamic flickering image pairs than by static side-by-side images, although there was no difference in accuracy.
UR - http://www.scopus.com/inward/record.url?scp=84857447889&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84857447889&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2011.08.030
DO - 10.1016/j.ajo.2011.08.030
M3 - Article
C2 - 22019222
AN - SCOPUS:84857447889
VL - 153
SP - 544
EP - 551
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 3
ER -