Evaluation of management of uncomplicated community-acquired pneumonia

A retrospective assessment

Thomas L. Walsh, Briana E. Di Silvio, Daniel Speredelozzi, Crystal D. Hammer, Kurt Hu, Rasha Abdulmassih, Jina Makadia, Rikinder Sandhu, Mouhib Naddour, Swati Vishwanathan, Noreen H. Chan-Tompkins, Tamara L. Trienski, Matthew A. Moffa, Derek N. Bremmer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Community-acquired pneumonia (CAP) remains a leading cause of hospitalization andmortality in the United States. Studies have shown that interventions such as shorter antibiotic therapy and early intravenous (IV) to oral conversion can be safely performed.We evaluated areas of improvement at our institutions that could help optimize patient managementwhile reducing collateral damage associatedwith excessive antibiotic usage. Methods: In this retrospective analysis, all patients aged 18 years and older with a primary International Classification of Diseases, Ninth Revision code for CAP admitted from March 1, 2014, to October 31, 2014, were analyzed. The primary outcome was duration of antibiotic therapy for uncomplicated CAP (appropriate treatment duration defined as 7 days or less). Secondary objectives included duration of IVantibiotic therapy, duration of inpatient length of stay, and 30-day readmission rate related to CAP. Results: Of the 141 patients evaluated, 98 (69.5%) met inclusion criteria. The mean total duration of antibiotic therapy was 10.1 ± 3.4 days, and the mean duration of IV therapy was 4.9 ± 3.3 days. Only 26.5% of patients received 7 days or less of antibiotic therapy, whereas 38.8% received greater than 10 days of therapy. Conclusions: Our findings are concerning given the available data demonstrating that short-course therapy with 5 to 7 days is clinically as effective as long-course therapy and associated with fewer adverse events. The management of uncomplicatedCAP represents a significant opportunity for antimicrobial stewardship intervention.

Original languageEnglish (US)
Pages (from-to)71-75
Number of pages5
JournalInfectious Diseases in Clinical Practice
Volume25
Issue number2
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

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Pneumonia
Anti-Bacterial Agents
Therapeutics
International Classification of Diseases
Inpatients
Length of Stay
Hospitalization

Keywords

  • Antibiotic utilization
  • Community-acquired pneumonia
  • Respiratory tract infections

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Walsh, T. L., Di Silvio, B. E., Speredelozzi, D., Hammer, C. D., Hu, K., Abdulmassih, R., ... Bremmer, D. N. (2017). Evaluation of management of uncomplicated community-acquired pneumonia: A retrospective assessment. Infectious Diseases in Clinical Practice, 25(2), 71-75. https://doi.org/10.1097/IPC.0000000000000468

Evaluation of management of uncomplicated community-acquired pneumonia : A retrospective assessment. / Walsh, Thomas L.; Di Silvio, Briana E.; Speredelozzi, Daniel; Hammer, Crystal D.; Hu, Kurt; Abdulmassih, Rasha; Makadia, Jina; Sandhu, Rikinder; Naddour, Mouhib; Vishwanathan, Swati; Chan-Tompkins, Noreen H.; Trienski, Tamara L.; Moffa, Matthew A.; Bremmer, Derek N.

In: Infectious Diseases in Clinical Practice, Vol. 25, No. 2, 01.03.2017, p. 71-75.

Research output: Contribution to journalArticle

Walsh, TL, Di Silvio, BE, Speredelozzi, D, Hammer, CD, Hu, K, Abdulmassih, R, Makadia, J, Sandhu, R, Naddour, M, Vishwanathan, S, Chan-Tompkins, NH, Trienski, TL, Moffa, MA & Bremmer, DN 2017, 'Evaluation of management of uncomplicated community-acquired pneumonia: A retrospective assessment', Infectious Diseases in Clinical Practice, vol. 25, no. 2, pp. 71-75. https://doi.org/10.1097/IPC.0000000000000468
Walsh, Thomas L. ; Di Silvio, Briana E. ; Speredelozzi, Daniel ; Hammer, Crystal D. ; Hu, Kurt ; Abdulmassih, Rasha ; Makadia, Jina ; Sandhu, Rikinder ; Naddour, Mouhib ; Vishwanathan, Swati ; Chan-Tompkins, Noreen H. ; Trienski, Tamara L. ; Moffa, Matthew A. ; Bremmer, Derek N. / Evaluation of management of uncomplicated community-acquired pneumonia : A retrospective assessment. In: Infectious Diseases in Clinical Practice. 2017 ; Vol. 25, No. 2. pp. 71-75.
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AU - Di Silvio, Briana E.

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AU - Hammer, Crystal D.

AU - Hu, Kurt

AU - Abdulmassih, Rasha

AU - Makadia, Jina

AU - Sandhu, Rikinder

AU - Naddour, Mouhib

AU - Vishwanathan, Swati

AU - Chan-Tompkins, Noreen H.

AU - Trienski, Tamara L.

AU - Moffa, Matthew A.

AU - Bremmer, Derek N.

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