Evaluation of Adjuvant Radiation Therapy for Resected Gallbladder Carcinoma: A Multi-institutional Experience

Jingya Wang, Amol K. Narang, Elizabeth A. Sugar, Brandon Luber, Lauren M. Rosati, Charles C. Hsu, Clifton D. Fuller, Timothy M. Pawlik, Robert C. Miller, Brian G. Czito, Richard Tuli, Christopher H. Crane, Edgar Ben-Josef, Charles Thomas, Joseph M. Herman

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Purpose: The role of adjuvant radiation for gallbladder carcinoma (GBC) is uncertain. We combine the experience of six National Cancer Institute-designated cancer centers to explore the impact of adjuvant radiation following oncologic resection of GBC. Methods: Patients who underwent extended surgery for GBC at Johns Hopkins, Mayo Clinic, Duke University, Oregon Health & Science University, University of Michigan, and University of Texas MD Anderson between 1985 and 2008 were reviewed. Patients with metastatic disease at surgery, gross residual disease, or missing pathologic information were excluded. Results: Of the 112 patients identified, 61 % received adjuvant radiation, 93 % of whom received concurrent chemotherapy. Median follow-up of surviving patients was 47.3 (range 2.2–167.7) months. Patients who received adjuvant radiation had a higher rate of advanced T-stage (57 vs. 16 %, p 

Original languageEnglish (US)
Pages (from-to)1100-1106
Number of pages7
JournalAnnals of Surgical Oncology
Volume22
DOIs
Publication statusPublished - Dec 1 2015

    Fingerprint

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Wang, J., Narang, A. K., Sugar, E. A., Luber, B., Rosati, L. M., Hsu, C. C., ... Herman, J. M. (2015). Evaluation of Adjuvant Radiation Therapy for Resected Gallbladder Carcinoma: A Multi-institutional Experience. Annals of Surgical Oncology, 22, 1100-1106. https://doi.org/10.1245/s10434-015-4685-y