Evaluation of a dispensing instrument (Dynatech MIC-2000) for preparing microtiter antibiotic plates and testing their potency during storage

P. R B McMaster, E. A. Robertson, F. G. Witebsky, James Maclowry

Research output: Contribution to journalArticle

9 Scopus citations


The MIC-2000 96-channel dispenser was evaluated for accuracy and repeatability of dispensing 50-μl volumes of water. It was found to perform within the manufacturer's specifications for accuracy of ±5%, but not within the limits for repeatability of ±1%. Overall, instrument performance was found to be satisfactory for the antimicrobial susceptibility testing technique which has been implemented in this laboratory. A method is suggested for simple evaluation of the volumes dispensed. A variety of antibiotics may be stored in Trypticase soy broth in microtiter plates without loss of potency for periods of at least 2 weeks at -20°C and 4 months at -70°C.

Original languageEnglish (US)
Pages (from-to)842-844
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Issue number5
Publication statusPublished - 1978
Externally publishedYes


ASJC Scopus subject areas

  • Pharmacology (medical)

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