@article{da38d0d3426f460cb21b288af1476cf4,
title = "European league against rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies",
abstract = "Background: Psoriatic arthritis (PsA) is a clinically heterogeneous disease. Clear consensual treatment guidance focused on the musculoskeletal manifestations of PsA would be advantageous. The authors present European League Against Rheumatism (EULAR) recommendations for the treatment of PsA with systemic or local (non-topical) symptomatic and disease-modifying antirheumatic drugs (DMARD). Methods: The recommendations are based on evidence from systematic literature reviews performed for non-steroidal anti-inflammatory drugs (NSAID), glucocorticoids, synthetic DMARD and biological DMARD. This evidence was discussed, summarised and recommendations were formulated by a task force comprising 35 representatives, and providing levels of evidence, strength of recommendations and levels of agreement. Results: Ten recommendations were developed for treatment from NSAID through synthetic DMARD to biological agents, accounting for articular and extra-articular manifestations of PsA. Five overarching principles and a research agenda were defined. Conclusion: These recommendations are intended to provide rheumatologists, patients and other stakeholders with a consensus on the pharmacological treatment of PsA and strategies to reach optimal outcomes, based on combining evidence and expert opinion. The research agenda informs directions within EULAR and other communities interested in PsA.",
author = "Laure Gossec and Smolen, {J. S.} and C. Gaujoux-Viala and Z. Ash and H. Marzo-Ortega and {Van Der Heijde}, D. and O. FitzGerald and D. Aletaha and P. Balint and D. Boumpas and J. Braun and Breedveld, {F. C.} and G. Burmester and Ca{\~n}ete, {J. D.} and {De Wit}, M. and H. Dagfinrud and {De Vlam}, K. and M. Dougados and P. Helliwell and A. Kavanaugh and Kvien, {T. K.} and R. Landew{\'e} and T. Luger and M. Maccarone and D. McGonagle and N. McHugh and McInnes, {I. B.} and C. Ritchlin and J. Sieper and Tak, {P. P.} and G. Valesini and J. Vencovsky and Winthrop, {K. L.} and A. Zink and P. Emery",
note = "Funding Information: R.K., F.S.-S., H.E.J., L.G.-S., D.J.-L., F.B., A.J., E.K., and E.R.B.M. acknowledge support from the European Commission 7th Framework Programme: ?Tailored-Treatment?, EU Grant Agreement No.: HEALTH-F3-602860-2013. Swedish V?stra G?taland regional funding, project nos. ALFGBG-437221 supported R.K., F.S.-S., E.R.B.M. and ALFGBG-720761 supported R.K., F.S.-S., L.G.-S., and E.R.B.M. The Swedish V?stra G?taland Region, FoU grant number VGFOUREG-665141 and Lab Medicine Project number 51060-6258 supported (R.K., S.S., E.K., and E.R.B.M.). F.S.-S., H.E.J., D.J.-L., S.S., and E.R.B.M. acknowledge support from the Swedish V?stra G?taland Region, Lab Medicine Project number 51060-6268. R.K., F.S.-S., D.J.-L., A.J., E.K., and E.R.B.M. acknowledge support from the Center for Antibiotic Resistance Research (CARe) at the University of Gothenburg. R.K. and D.J.-L. were supported by stipends for Basic and Advanced Research from the Culture Collection of the University of Gothenburg (CCUG), through the Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg. The authors have declared a conflict of interest. Funding Information: Acknowledgments—The CCUG and the staff are acknowledged for providing reference strains and expert characterization analyses. The CCUG is supported by the Department of Clinical Microbiology, Sahl-grenska University Hospital. The staff of the Bacteriology laboratory of the Department of Clinical Microbiology of Sahlgrenska University Hospital are acknowledged for providing clinical samples and for expert identification analyses. We acknowledge the expertise and effort of the Proteomics Core Facility, Sahlgrenska Academy, University of Gothenburg. We thank Dr. Vincent Collins, BioKonsult G{\"o}te-borg, for critical discussions and proof-reading the manuscript. Beatriz Pi{\~n}eiro Iglesias and Shora Yazdanshenas are acknowledged for technical assistance. Chantal van Houten and Louis Bont at the Division of Pediatric Immunology and Infectious Diseases, University Medical Centre Utrecht, The Netherlands and Dan En-gelhardt at the Division of Pediatric Infectious Disease Unit, Hadas-sah-Hebrew University Medical Centre, Jerusalem, Israel, are acknowledged for fruitful discussion regarding collection of clinical samples during the Tailored Treatment project. Authors A.K. and R.K. are affiliated to a company, Nanoxis Consulting AB. The Company did not have influence on the collection, analysis, or interpretation of data, the writing of the paper, or the decision to submit for publication. Funding Information: * R.K., F.S.-S., H.E.J., L.G.-S., D.J.-L., F.B., A.J., E.K., and E.R.B.M. acknowledge support from the European Commission 7th Framework Programme: “Tailored-Treatment”, EU Grant Agreement No.: HEALTH-F3-602860-2013. Swedish V{\"a}stra G{\"o}taland regional funding, project nos. ALFGBG-437221 supported R.K., F.S.-S., E.R.B.M. and ALFGBG-720761 supported R.K., F.S.-S., L.G.-S., and E.R.B.M. The Swedish V{\"a}stra G{\"o}taland Region, FoU grant number VG-FOUREG-665141 and Lab Medicine Project number 51060-6258 supported (R.K., S.S., E.K., and E.R.B.M.). F.S.-S., H.E.J., D.J.-L., S.S., and E.R.B.M. acknowledge support from the Swedish V{\"a}stra G{\"o}taland Region, Lab Medicine Project number 51060-6268. R.K., F.S.-S., D.J.-L., A.J., E.K., and E.R.B.M. acknowledge support from the Center for Antibiotic Resistance Research (CARe) at the University of Gothenburg. R.K. and D.J.-L. were supported by stipends for Basic and Advanced Research from the Culture Collection of the University of Gothenburg (CCUG), through the Institute of Biomedicine, Sahlg-renska Academy, University of Gothenburg. The authors have declared a conflict of interest. □S This article contains supplemental material. §§§ To whom correspondence should be addressed. Tel.: +46 708 344594; E-mail: roger.karlsson@nanoxisconsulting.com. ¶¶¶ These authors contributed equally to the study.",
year = "2012",
month = jan,
doi = "10.1136/annrheumdis-2011-200350",
language = "English (US)",
volume = "71",
pages = "4--12",
journal = "Annals of the rheumatic diseases",
issn = "0003-4967",
publisher = "BMJ Publishing Group",
number = "1",
}