Ethnic disparities in conditional survival of patients with non-small cell lung cancer

Samuel Wang, C. David Fuller, Charles Thomas

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32 Citations (Scopus)

Abstract

PURPOSE: Conditional survival (CS) is an accurate estimate of survival probability for patients who have already survived at least 1 year after diagnosis. The purpose of this study was to determine whether ethnicity plays a role in 5-year CS rates for patients with non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Using the Surveillance, Epidemiology, and End Results database, we analyzed 96,480 patients with NSCLC diagnosed between 1988 and 1995. Patients were divided into five ethnic groups: White (non-Hispanic), Hispanic, African American, Asian/Pacific Islander, and Native American/Alaskan. Using the life table method, we computed observed 5-year CS rates for patients who had already survived up to 5 years after diagnosis. Results were analyzed by stage, age, sex, and histology. RESULTS: In general, 5-year CS rates increase for all ethnicities as time from diagnosis increases, but African Americans continued to have lower CS rates compared with other ethnic groups, even up to 5 years from diagnosis. When analyzed by stage, Hispanics with stage IV disease showed the greatest improvement in CS rate, increasing to 73% at 5 years from diagnosis. Among patients older than 70 years, African Americans had the lowest CS at 5 years-only 28%, compared with 40% to 47% for other groups. When analyzed by histology, Hispanics with large cell carcinoma had the worst CS rate (35% at 5 years). CONCLUSION: For patients with NSCLC surviving a period of time after diagnosis, 5-year CS rates vary by ethnicity. CS can provide accurate prognostic information for patients with NSCLC who have already survived several years after diagnosis.

Original languageEnglish (US)
Pages (from-to)180-190
Number of pages11
JournalJournal of Thoracic Oncology
Volume2
Issue number3
DOIs
StatePublished - Mar 2007

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Non-Small Cell Lung Carcinoma
Survival Rate
Survival
Hispanic Americans
African Americans
Ethnic Groups
Histology
Oceanic Ancestry Group
Large Cell Carcinoma
Life Tables
North American Indians
Epidemiology
Databases

Keywords

  • Ethnicity
  • Lung cancer
  • Non-small cell lung cancer
  • Race
  • Survival

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

Ethnic disparities in conditional survival of patients with non-small cell lung cancer. / Wang, Samuel; Fuller, C. David; Thomas, Charles.

In: Journal of Thoracic Oncology, Vol. 2, No. 3, 03.2007, p. 180-190.

Research output: Contribution to journalArticle

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