Estrogen stimulates synthesis of progesterone by porcine granulosa cells in tissue culture. This enhancement is inhibited by cycloheximide, suggesting that protein synthesis is required for the effect. Estrogen is synergistic with hCG in increasing progesterone synthesis. Sequential treatment with hCG followed by estradiol causes maximal stimulation of progesterone production.
|Original language||English (US)|
|Number of pages||7|
|Journal||Biochemical and Biophysical Research Communications|
|Publication status||Published - Jul 11 1972|
ASJC Scopus subject areas
- Molecular Biology