Estrogen stimulation of progesterone synthesis by porcine granulosa cells in culture

Robert L. Goldenberg, William E. Bridson, Peter O. Kohler

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Estrogen stimulates synthesis of progesterone by porcine granulosa cells in tissue culture. This enhancement is inhibited by cycloheximide, suggesting that protein synthesis is required for the effect. Estrogen is synergistic with hCG in increasing progesterone synthesis. Sequential treatment with hCG followed by estradiol causes maximal stimulation of progesterone production.

Original languageEnglish (US)
Pages (from-to)101-107
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume48
Issue number1
DOIs
StatePublished - Jul 11 1972

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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