Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

George R. Wandling; Mansi Parikh; Christopher Robinson; Sudeep N. Pramanik; Kenneth M. Goins; John E. Sutphin; Wallace L.M. Alward; Emily C. Greenlee; Young H. Kwon; Michael D. Wagoner

doi:10.1097/ICO.0b013e3181cc7b02

Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

George R. Wandling, Mansi Parikh, Christopher Robinson, Sudeep N. Pramanik, Kenneth M. Goins, John E. Sutphin, Wallace L.M. Alward, Emily C. Greenlee, Young H. Kwon, Michael D. Wagoner

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Purpose: To determine the prevalence and risk factors for escalation of glaucoma therapy after deep lamellar endothelial keratoplasty (DLEK). Methods: Retrospective review of every case of DLEK performed at a tertiary care facility between December 1, 2003 and January 31, 2006. Results: Eighty eyes met the inclusion criteria. Escalation of glaucoma therapy occurred in 13 eyes (16.3%) during a mean follow-up period of 27.1 months. Ten eyes required additional topical medical therapy, and 3 eyes required surgical intervention. Glaucoma therapy escalation was significantly associated with preexisting glaucoma (42.9% vs. 10.6%; P = 0.008). Conclusion: Escalation of glaucoma therapy is not uncommon after DLEK, especially in eyes with preexisting glaucoma.

Original language	English (US)
Pages (from-to)	991-995
Number of pages	5
Journal	Cornea
Volume	29
Issue number	9
DOIs	https://doi.org/10.1097/ICO.0b013e3181cc7b02
State	Published - Sep 2010
Externally published	Yes

Keywords

deep lamellar endothelial keratoplasty
endothelial keratoplasty
glaucoma
graft failure

ASJC Scopus subject areas

Ophthalmology

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10.1097/ICO.0b013e3181cc7b02

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title = "Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty",

abstract = "Purpose: To determine the prevalence and risk factors for escalation of glaucoma therapy after deep lamellar endothelial keratoplasty (DLEK). Methods: Retrospective review of every case of DLEK performed at a tertiary care facility between December 1, 2003 and January 31, 2006. Results: Eighty eyes met the inclusion criteria. Escalation of glaucoma therapy occurred in 13 eyes (16.3%) during a mean follow-up period of 27.1 months. Ten eyes required additional topical medical therapy, and 3 eyes required surgical intervention. Glaucoma therapy escalation was significantly associated with preexisting glaucoma (42.9% vs. 10.6%; P = 0.008). Conclusion: Escalation of glaucoma therapy is not uncommon after DLEK, especially in eyes with preexisting glaucoma.",

keywords = "deep lamellar endothelial keratoplasty, endothelial keratoplasty, glaucoma, graft failure",

author = "Wandling, {George R.} and Mansi Parikh and Christopher Robinson and Pramanik, {Sudeep N.} and Goins, {Kenneth M.} and Sutphin, {John E.} and Alward, {Wallace L.M.} and Greenlee, {Emily C.} and Kwon, {Young H.} and Wagoner, {Michael D.}",

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doi = "10.1097/ICO.0b013e3181cc7b02",

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T1 - Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

AU - Wandling, George R.

AU - Parikh, Mansi

AU - Robinson, Christopher

AU - Pramanik, Sudeep N.

AU - Goins, Kenneth M.

AU - Sutphin, John E.

AU - Alward, Wallace L.M.

AU - Greenlee, Emily C.

AU - Kwon, Young H.

AU - Wagoner, Michael D.

PY - 2010/9

Y1 - 2010/9

N2 - Purpose: To determine the prevalence and risk factors for escalation of glaucoma therapy after deep lamellar endothelial keratoplasty (DLEK). Methods: Retrospective review of every case of DLEK performed at a tertiary care facility between December 1, 2003 and January 31, 2006. Results: Eighty eyes met the inclusion criteria. Escalation of glaucoma therapy occurred in 13 eyes (16.3%) during a mean follow-up period of 27.1 months. Ten eyes required additional topical medical therapy, and 3 eyes required surgical intervention. Glaucoma therapy escalation was significantly associated with preexisting glaucoma (42.9% vs. 10.6%; P = 0.008). Conclusion: Escalation of glaucoma therapy is not uncommon after DLEK, especially in eyes with preexisting glaucoma.

AB - Purpose: To determine the prevalence and risk factors for escalation of glaucoma therapy after deep lamellar endothelial keratoplasty (DLEK). Methods: Retrospective review of every case of DLEK performed at a tertiary care facility between December 1, 2003 and January 31, 2006. Results: Eighty eyes met the inclusion criteria. Escalation of glaucoma therapy occurred in 13 eyes (16.3%) during a mean follow-up period of 27.1 months. Ten eyes required additional topical medical therapy, and 3 eyes required surgical intervention. Glaucoma therapy escalation was significantly associated with preexisting glaucoma (42.9% vs. 10.6%; P = 0.008). Conclusion: Escalation of glaucoma therapy is not uncommon after DLEK, especially in eyes with preexisting glaucoma.

KW - deep lamellar endothelial keratoplasty

KW - endothelial keratoplasty

KW - glaucoma

KW - graft failure

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JO - Cornea

JF - Cornea

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ER -

Escalation of glaucoma therapy after deep lamellar endothelial keratoplasty

Abstract

Keywords

ASJC Scopus subject areas

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