Epithelial ovarian cancer

Tanja Pejovic, Kunle Odunsi, Matthew L. Anderson

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Over the past decade, medicine has witnessed an explosion of new insights into the genomic events important for determining a woman’s susceptibility to ovarian cancer. Many of these insights also play a key role in determining clinical ovarian cancer outcomes. This chapter reviews our rapidly evolving understanding of these events. It places particular emphasis on those insights, such as our understanding of inherited syndromes of breast and ovarian cancer, that have dramatically expanded options for ovarian cancer prevention and treatment.

Original languageEnglish (US)
Title of host publicationGenomic and Precision Medicine
Subtitle of host publicationOncology, Third Edition
PublisherElsevier
Pages173-190
Number of pages18
ISBN (Electronic)9780128006849
ISBN (Print)9780128006535
DOIs
StatePublished - Jan 1 2022

Keywords

  • angiogenesis
  • BRCA1/2
  • Epithelial ovarian cancer
  • homologous recombination deficiency
  • immune response
  • PARP inhibitors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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