@article{712465b0e45f4e1a959a36d27000c972,
title = "Epigenomic inactivation of RasGAPs activates RAS signaling in a subset of luminal B breast cancers",
abstract = "Invasion and metastasis of a subset of aggressive luminal B breast cancers is driven by the concomitant inactivation of the RasGAPs DAB2IP and RASAL2. Inactivation of both proteins increases RAS activity and drives invasion, whereas inactivation of DAB2IP specifically promotes NF-κB-mediated epithelial-mesenchymal transition.",
author = "Rosalie Sears and Gray, {Joe W.}",
note = "Funding Information: This work was supported by NIH(National Institutes of Health)grants U54 CA112970 (J.W. Gray) and R01 CA196228 (R. Sears). Publisher Copyright: {\textcopyright} 2017 American Association for Cancer Research. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "2017",
month = feb,
doi = "10.1158/2159-8290.CD-16-1423",
language = "English (US)",
volume = "7",
pages = "131--133",
journal = "Cancer Discovery",
issn = "2159-8274",
publisher = "American Association for Cancer Research Inc.",
number = "2",
}