Epidemiology of atopic dermatitis in adults: Results from an international survey

S. Barbarot, S. Auziere, A. Gadkari, G. Girolomoni, L. Puig, Eric Simpson, D. J. Margolis, M. de Bruin-Weller, L. Eckert

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Background: There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD). Objective: To estimate the prevalence of AD in adults and by disease severity. Methods: This international, cross-sectional, web-based survey was performed in the United States, Canada, France, Germany, Italy, Spain, United Kingdom, and Japan. Adult members of online respondent panels were sent a questionnaire for AD identification and severity assessment; demographic quotas ensured population representativeness for each country. A diagnosis of AD required subjects to be positive on the modified UK Working Party/ISAAC criteria and self-report of ever having an AD diagnosis by a physician. The proportion of subjects with AD who reported being treated for their condition was determined and also used to estimate prevalence. Severity scales were Patient-Oriented SCORAD, Patient-Orientated Eczema Measure, and Patient Global Assessment. Results: Among participants by region, the point prevalence of adult AD in the overall/treated populations was 4.9%/3.9% in the US, 3.5%/2.6% in Canada, 4.4%/3.5% in the EU, and 2.1%/1.5% in Japan. The prevalence was generally lower for males vs females, and decreased with age. Regional variability was observed within countries. Severity varied by scale and region; however, regardless of the scale or region, proportion of subjects reporting severe disease was lower than mild or moderate disease. Conclusions: Prevalence of adult AD ranged from 2.1% to 4.9% across countries. Severe AD represented a small proportion of the overall AD population regardless of measure or region.

Original languageEnglish (US)
Pages (from-to)1284-1293
Number of pages10
JournalAllergy: European Journal of Allergy and Clinical Immunology
Volume73
Issue number6
DOIs
StatePublished - Jun 1 2018

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Atopic Dermatitis
Epidemiology
Canada
Japan
Surveys and Questionnaires
Population
Eczema
Spain
Self Report
Italy
France
Germany
Demography
Physicians

Keywords

  • atopic dermatitis
  • epidemiology
  • prevalence
  • severity

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Epidemiology of atopic dermatitis in adults : Results from an international survey. / Barbarot, S.; Auziere, S.; Gadkari, A.; Girolomoni, G.; Puig, L.; Simpson, Eric; Margolis, D. J.; de Bruin-Weller, M.; Eckert, L.

In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 73, No. 6, 01.06.2018, p. 1284-1293.

Research output: Contribution to journalArticle

Barbarot, S, Auziere, S, Gadkari, A, Girolomoni, G, Puig, L, Simpson, E, Margolis, DJ, de Bruin-Weller, M & Eckert, L 2018, 'Epidemiology of atopic dermatitis in adults: Results from an international survey', Allergy: European Journal of Allergy and Clinical Immunology, vol. 73, no. 6, pp. 1284-1293. https://doi.org/10.1111/all.13401
Barbarot, S. ; Auziere, S. ; Gadkari, A. ; Girolomoni, G. ; Puig, L. ; Simpson, Eric ; Margolis, D. J. ; de Bruin-Weller, M. ; Eckert, L. / Epidemiology of atopic dermatitis in adults : Results from an international survey. In: Allergy: European Journal of Allergy and Clinical Immunology. 2018 ; Vol. 73, No. 6. pp. 1284-1293.
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abstract = "Background: There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD). Objective: To estimate the prevalence of AD in adults and by disease severity. Methods: This international, cross-sectional, web-based survey was performed in the United States, Canada, France, Germany, Italy, Spain, United Kingdom, and Japan. Adult members of online respondent panels were sent a questionnaire for AD identification and severity assessment; demographic quotas ensured population representativeness for each country. A diagnosis of AD required subjects to be positive on the modified UK Working Party/ISAAC criteria and self-report of ever having an AD diagnosis by a physician. The proportion of subjects with AD who reported being treated for their condition was determined and also used to estimate prevalence. Severity scales were Patient-Oriented SCORAD, Patient-Orientated Eczema Measure, and Patient Global Assessment. Results: Among participants by region, the point prevalence of adult AD in the overall/treated populations was 4.9{\%}/3.9{\%} in the US, 3.5{\%}/2.6{\%} in Canada, 4.4{\%}/3.5{\%} in the EU, and 2.1{\%}/1.5{\%} in Japan. The prevalence was generally lower for males vs females, and decreased with age. Regional variability was observed within countries. Severity varied by scale and region; however, regardless of the scale or region, proportion of subjects reporting severe disease was lower than mild or moderate disease. Conclusions: Prevalence of adult AD ranged from 2.1{\%} to 4.9{\%} across countries. Severe AD represented a small proportion of the overall AD population regardless of measure or region.",
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AU - Puig, L.

AU - Simpson, Eric

AU - Margolis, D. J.

AU - de Bruin-Weller, M.

AU - Eckert, L.

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N2 - Background: There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD). Objective: To estimate the prevalence of AD in adults and by disease severity. Methods: This international, cross-sectional, web-based survey was performed in the United States, Canada, France, Germany, Italy, Spain, United Kingdom, and Japan. Adult members of online respondent panels were sent a questionnaire for AD identification and severity assessment; demographic quotas ensured population representativeness for each country. A diagnosis of AD required subjects to be positive on the modified UK Working Party/ISAAC criteria and self-report of ever having an AD diagnosis by a physician. The proportion of subjects with AD who reported being treated for their condition was determined and also used to estimate prevalence. Severity scales were Patient-Oriented SCORAD, Patient-Orientated Eczema Measure, and Patient Global Assessment. Results: Among participants by region, the point prevalence of adult AD in the overall/treated populations was 4.9%/3.9% in the US, 3.5%/2.6% in Canada, 4.4%/3.5% in the EU, and 2.1%/1.5% in Japan. The prevalence was generally lower for males vs females, and decreased with age. Regional variability was observed within countries. Severity varied by scale and region; however, regardless of the scale or region, proportion of subjects reporting severe disease was lower than mild or moderate disease. Conclusions: Prevalence of adult AD ranged from 2.1% to 4.9% across countries. Severe AD represented a small proportion of the overall AD population regardless of measure or region.

AB - Background: There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD). Objective: To estimate the prevalence of AD in adults and by disease severity. Methods: This international, cross-sectional, web-based survey was performed in the United States, Canada, France, Germany, Italy, Spain, United Kingdom, and Japan. Adult members of online respondent panels were sent a questionnaire for AD identification and severity assessment; demographic quotas ensured population representativeness for each country. A diagnosis of AD required subjects to be positive on the modified UK Working Party/ISAAC criteria and self-report of ever having an AD diagnosis by a physician. The proportion of subjects with AD who reported being treated for their condition was determined and also used to estimate prevalence. Severity scales were Patient-Oriented SCORAD, Patient-Orientated Eczema Measure, and Patient Global Assessment. Results: Among participants by region, the point prevalence of adult AD in the overall/treated populations was 4.9%/3.9% in the US, 3.5%/2.6% in Canada, 4.4%/3.5% in the EU, and 2.1%/1.5% in Japan. The prevalence was generally lower for males vs females, and decreased with age. Regional variability was observed within countries. Severity varied by scale and region; however, regardless of the scale or region, proportion of subjects reporting severe disease was lower than mild or moderate disease. Conclusions: Prevalence of adult AD ranged from 2.1% to 4.9% across countries. Severe AD represented a small proportion of the overall AD population regardless of measure or region.

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