Epidemiology and association of vascular and valvular calcium quantified by multidetector computed tomography in elderly asymptomatic subjects

Ricardo C. Cury, Maros Ferencik, Udo Hoffmann, Ashley Ferullo, Fabian Moselewski, Suhny Abbara, Sarah L. Booth, Christopher J. O'Donnell, Thomas J. Brady, Stephan Achenbach

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    Abstract

    The epidemiology of and association between vascular and valvular calcium as quantified by multidetector computed tomography (MDCT) were studied in 416 elderly subjects with no history of coronary artery disease. Coronary calcium (CC), descending thoracic aortic calcium (DTAC), aortic valve calcium (AVC), and mitral valve calcium (MVC) were present in 282 (68%), 214 (51%), 152 (37%), and 68 (16%) subjects, respectively. Multiple logistic regression analysis showed that after adjusting for age and gender, subjects with AVC (odds ratio [OR] 2.3), MVC (OR 2.81), and DTAC (OR 2.79) were independently and significantly more likely to have CC. Further evidence is provided for the notion that calcifications in those regions are associated and that MDCT can be used as a tool for the global assessment of vascular and valvular calcium.

    Original languageEnglish (US)
    Pages (from-to)348-351
    Number of pages4
    JournalAmerican Journal of Cardiology
    Volume94
    Issue number3
    DOIs
    StatePublished - Aug 1 2004

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine

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  • Cite this

    Cury, R. C., Ferencik, M., Hoffmann, U., Ferullo, A., Moselewski, F., Abbara, S., Booth, S. L., O'Donnell, C. J., Brady, T. J., & Achenbach, S. (2004). Epidemiology and association of vascular and valvular calcium quantified by multidetector computed tomography in elderly asymptomatic subjects. American Journal of Cardiology, 94(3), 348-351. https://doi.org/10.1016/j.amjcard.2004.04.032