Epidemic and sporadic cases of nontuberculous mycobacterial keratitis associated with laser in situ keratomileusis

Kevin L. Winthrop, Ellen B. Steinberg, Gary Holmes, Marion A. Kainer, S. B. Werner, Andrea Winquist, Duc J. Vugia

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

PURPOSE: To report national case-finding results for nontuberculous mycobacterial keratitis and describe its association with laser in situ keratomileusis (LASIK). DESIGN: Enhanced passive disease reporting. METHODS: In April 2001, we investigated a California cluster of Mycobacterium chelonae keratitis associated with hyperopic LASIK using a contact lens mask. To identify other possibly related cases, the American Academy of Ophthalmology e-mailed its members asking them to report recent cases of nontuberculous mycobacterial keratitis to the Centers for Disease Control and Prevention. RESULTS: Forty-three additional cases of keratitis were reported (onsets between August 2000 and June 2001). Of these, 31 occurred as part of two unrelated LASIK-associated outbreaks. The 12 other reported cases occurred in sporadic fashion. Of the latter cases, 4 were associated with LASIK surgery. None of the reported cases were related to the M. chelonae cluster in California. CONCLUSIONS: Laser in situ keratomileusis-associated keratitis with nontuberculous mycobacteria may be more common than previously known.

Original languageEnglish (US)
Pages (from-to)223-224
Number of pages2
JournalAmerican journal of ophthalmology
Volume135
Issue number2
DOIs
StatePublished - Feb 1 2003

ASJC Scopus subject areas

  • Ophthalmology

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