Abstract
Sympathetic nerve responses to posterior hypothalamic stimulation were recorded from the preceliac splanchnic nerve in spontaneously hypertensive rats (SHR) and normotensive, Wistar-Kyoto rats (WKY) following interruption of the baroreceptor reflex. Responses to identical stimulation were then recorded following ganglionic blockade with hexamethonium. The enhanced preganglionic sympathetic nerve responses measured in SHR indicate that the sympathetic hyperresponsiveness in this hypertensive strain occurs, at least in part, at a site within the central nervous system.
Original language | English (US) |
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Pages (from-to) | 152-155 |
Number of pages | 4 |
Journal | Brain research |
Volume | 296 |
Issue number | 1 |
DOIs | |
State | Published - Mar 26 1984 |
Externally published | Yes |
Keywords
- ganglionic blockade
- posterior hypothalamic stimulation
- preceliac splanchnic nerve
- spontaneously hypertensive rat
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology