Enhanced electron transfer and lauric acid hydroxylation by site-directed mutagenesis of CYP119

Medicine & Life Sciences

• Sulfolobus solfataricus CYP119 protein 100%
• putidaredoxin 89%
• lauric acid 66%
• Hydroxylation 49%
• Site-Directed Mutagenesis 46%
• Electrons 34%
• Cytochrome P-450 Enzyme System 31%
• putidaredoxin reductase 22%
• Camphor 5-Monooxygenase 20%
• Fatty Acids 18%
• Sequence Alignment 13%
• Mutation 12%
• Heme 12%
• Mutation Rate 11%
• Mutagenesis 10%
• Oxidation-Reduction 10%
• Binding Sites 8%
• Proteins 7%

Engineering & Materials Science

• Cytochrome P-450 Enzyme System 79%
• Hydroxylation 78%
• Mutagenesis 68%
• Electrons 43%
• Acids 39%
• Fatty acids 35%
• Proteins 26%
• Oxidoreductases 21%
• Binding sites 20%
• Oxidation-Reduction 18%
• Crystal structure 18%
• Catalyst activity 17%
• Substrates 10%
• Engineers 10%

Chemical Compounds

• Putidaredoxin 71%
• Site-Directed Mutagenesis 45%
• Electron Transfer 30%
• Mutation 22%
• Acid 15%
• Fatty Acid 14%
• Spin State 9%
• Cytochrome P450 9%
• Heme 8%
• Binding Site 6%
• Crystal Structure 4%