Endoscopic Sclerotherapy for Esophageal Variceal Hemorrhage

Robert S. Gordon, Bennett M. Derby, John P. Cello, James H. Grendell, Richard A. Crass, Donald Trunkey, Thorkild I.a. Sørensen, Peter Matzen, Flemming Burcharth, Bjørn Andersen

Research output: Contribution to journalLetter

2 Citations (Scopus)

Abstract

To the Editor: How could the Journal, which six years earlier published a landmark paper on the need for adequate sample size in controlled clinical trials,1 now publish without comment the paper by Cello et al. (Dec. 20 issue),2 which overinterprets the negative results of a trial based on a very modest number of patients? These authors randomly assigned 52 patients to one of two alternative forms of treatment and “failed to demonstrate any significant difference in long-term survival. …” They go on to state that “acute and vigorously repeated endoscopic sclerotherapy is at least as good as, and.

Original languageEnglish (US)
Pages (from-to)989-990
Number of pages2
JournalNew England Journal of Medicine
Volume312
Issue number15
DOIs
StatePublished - Apr 11 1985
Externally publishedYes

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Sclerotherapy
Hemorrhage
Controlled Clinical Trials
Sample Size
Survival
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Gordon, R. S., Derby, B. M., Cello, J. P., Grendell, J. H., Crass, R. A., Trunkey, D., ... Andersen, B. (1985). Endoscopic Sclerotherapy for Esophageal Variceal Hemorrhage. New England Journal of Medicine, 312(15), 989-990. https://doi.org/10.1056/NEJM198504113121513

Endoscopic Sclerotherapy for Esophageal Variceal Hemorrhage. / Gordon, Robert S.; Derby, Bennett M.; Cello, John P.; Grendell, James H.; Crass, Richard A.; Trunkey, Donald; Sørensen, Thorkild I.a.; Matzen, Peter; Burcharth, Flemming; Andersen, Bjørn.

In: New England Journal of Medicine, Vol. 312, No. 15, 11.04.1985, p. 989-990.

Research output: Contribution to journalLetter

Gordon, RS, Derby, BM, Cello, JP, Grendell, JH, Crass, RA, Trunkey, D, Sørensen, TIA, Matzen, P, Burcharth, F & Andersen, B 1985, 'Endoscopic Sclerotherapy for Esophageal Variceal Hemorrhage', New England Journal of Medicine, vol. 312, no. 15, pp. 989-990. https://doi.org/10.1056/NEJM198504113121513
Gordon, Robert S. ; Derby, Bennett M. ; Cello, John P. ; Grendell, James H. ; Crass, Richard A. ; Trunkey, Donald ; Sørensen, Thorkild I.a. ; Matzen, Peter ; Burcharth, Flemming ; Andersen, Bjørn. / Endoscopic Sclerotherapy for Esophageal Variceal Hemorrhage. In: New England Journal of Medicine. 1985 ; Vol. 312, No. 15. pp. 989-990.
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