Endoscopic retrograde cholangiopancreatography in the pediatric population is safe and efficacious

Brintha K. Enestvedt, Christina Tofani, Dale Y. Lee, Maíre Abraham, Pari Shah, Vinay Chandrasekhara, Gregory G. Ginsberg, William Long, Nuzhat Ahmad, David L. Jaffe, Petar Mamula, Michael L. Kochman

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

BACKGROUND:: Endoscopic retrograde cholangiopancreatography (ERCP) is increasingly being used in the evaluation and management of biliary and pancreatic disorders in children. The aim of this study was to review the pediatric ERCP experience of a large academic referral center affiliated with a tertiary care children's hospital. METHODS:: This is a retrospective review of medical records, endoscopic and operative reports, and radiography of those patients ages 0 to 21 years who underwent ERCP for any indication between 1993 and 2011 at a tertiary referral center affiliated with a large urban pediatric hospital. ERCP technical success was defined as cannulation of the desired duct. Serious adverse events included bleeding, perforation, pancreatitis, or death. RESULTS:: Four hundred twenty-nine ERCPs were performed on 296 patients. The mean age was 14.9±4.8 years (3 months-21 years); 51.1% were boys. Patients with a history of previous liver transplant comprised 13.1% (56) of all ERCPs. Abnormal liver chemistries or suspected choledocholithiasis accounted for half of the indications. A therapeutic intervention was performed in 64.1%. Technical success was achieved in 95.2% of ERCPs. Serious adverse events occurred in 7.7%. CONCLUSIONS:: Pediatric ERCP is highly efficacious in the pediatric population, with the rates of technical success and use of therapeutic interventions mirroring those in adults. There is a low overall rate of serious adverse events. The overall efficacy and safety support the performance of pediatric ERCP by experienced endoscopists at high-volume centers.

Original languageEnglish (US)
Pages (from-to)649-654
Number of pages6
JournalJournal of pediatric gastroenterology and nutrition
Volume57
Issue number5
DOIs
StatePublished - Nov 1 2013

Keywords

  • children
  • pancreaticobiliary disease
  • pediatric ERCP

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

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    Enestvedt, B. K., Tofani, C., Lee, D. Y., Abraham, M., Shah, P., Chandrasekhara, V., Ginsberg, G. G., Long, W., Ahmad, N., Jaffe, D. L., Mamula, P., & Kochman, M. L. (2013). Endoscopic retrograde cholangiopancreatography in the pediatric population is safe and efficacious. Journal of pediatric gastroenterology and nutrition, 57(5), 649-654. https://doi.org/10.1097/MPG.0b013e31829e0bb6