Endogenous circadian control of the human autonomic nervous system

M. F. Hilton, M. U. Umali, C. A. Czeisler, J. K. Wyatt, Steven Shea

Research output: Chapter in Book/Report/Conference proceedingConference contribution

34 Citations (Scopus)

Abstract

To determine if an endogenous circadian rhythmicity, independent from sleep/wake cycles, exists in autonomic nervous system (ANS) function, heart rate variability analysis of electrocardiogram R-R intervals was applied to data collected during a 27-day forced desynchrony protocol. Results during wakefulness indicate that the circadian pacemaker may control both the sympathetic and vagal limbs of the ANS. Vagal tone was maximal during the circadian phase corresponding to the usual sleep episode (although these measurements were made in the absence of sleep) with an acrophase at 4 AM to 5 AM. Sympathovagal balance was maximal between 9 AM and 1 PM. These endogenous circadian rhythms in ANS function may contribute to mortality from cardiovascular disease and nocturnal asthma.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
PublisherIEEE
Pages197-200
Number of pages4
StatePublished - 2000
Externally publishedYes

Fingerprint

Autonomic Nervous System
Neurology
Sleep
Pacemakers
Wakefulness
Periodicity
Circadian Rhythm
Electrocardiography
Cardiovascular Diseases
Asthma
Extremities
Heart Rate
Mortality

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

Cite this

Hilton, M. F., Umali, M. U., Czeisler, C. A., Wyatt, J. K., & Shea, S. (2000). Endogenous circadian control of the human autonomic nervous system. In Computers in Cardiology (pp. 197-200). IEEE.

Endogenous circadian control of the human autonomic nervous system. / Hilton, M. F.; Umali, M. U.; Czeisler, C. A.; Wyatt, J. K.; Shea, Steven.

Computers in Cardiology. IEEE, 2000. p. 197-200.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hilton, MF, Umali, MU, Czeisler, CA, Wyatt, JK & Shea, S 2000, Endogenous circadian control of the human autonomic nervous system. in Computers in Cardiology. IEEE, pp. 197-200.
Hilton MF, Umali MU, Czeisler CA, Wyatt JK, Shea S. Endogenous circadian control of the human autonomic nervous system. In Computers in Cardiology. IEEE. 2000. p. 197-200
Hilton, M. F. ; Umali, M. U. ; Czeisler, C. A. ; Wyatt, J. K. ; Shea, Steven. / Endogenous circadian control of the human autonomic nervous system. Computers in Cardiology. IEEE, 2000. pp. 197-200
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